Structure of PDB 1bi0 Chain A Binding Site BS01
Receptor Information
>1bi0 Chain A (length=214) Species:
1717
(Corynebacterium diphtheriae) [
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LVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERDGL
VVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEACR
WEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVPGTRVIDAATSMP
RKVRIVQINEIFQVETDQFTQLLDADIRVGSEVEIVDRHITLSHNGKDVE
LLDDLAHTIRIEEL
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
1bi0 Chain A Residue 291 [
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Receptor-Ligand Complex Structure
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PDB
1bi0
Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
H79 E83 H98
Binding residue
(residue number reindexed from 1)
H76 E80 H95
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
GO:0017124
SH3 domain binding
GO:0042802
identical protein binding
GO:0046914
transition metal ion binding
GO:0046983
protein dimerization activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
GO:0045892
negative regulation of DNA-templated transcription
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1bi0
,
PDBe:1bi0
,
PDBj:1bi0
PDBsum
1bi0
PubMed
9712865
UniProt
P0DJL7
|DTXR_CORDI Diphtheria toxin repressor (Gene Name=dtxR)
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