Structure of PDB 1bff Chain A Binding Site BS01

Receptor Information
>1bff Chain A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKG
VCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVA
LKRTGQYKLGSKTGPGQKAILFLPMSAKS
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain1bff Chain A Residue 156 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1bff X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		N35 R128 K133
Binding residue
(residue number reindexed from 1)		N10 R103 K108
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1bff, PDBe:1bff, PDBj:1bff
PDBsum1bff
PubMed15299950
UniProtP09038|FGF2_HUMAN Fibroblast growth factor 2 (Gene Name=FGF2)

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