Structure of PDB 1bci Chain A Binding Site BS01

Receptor Information
>1bci Chain A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNN
DINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVG
EKKEVPFIFNQVTEMVLEMSLEV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1bci Chain A Residue 139 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1bci Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2.
ResolutionN/A
Binding residue
(original residue number in PDB)		D40 T41 D43 N64 N65
Binding residue
(residue number reindexed from 1)		D25 T26 D28 N49 N50
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
3.1.1.5: lysophospholipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008289 lipid binding

View graph for
Molecular Function
External links
PDB RCSB:1bci, PDBe:1bci, PDBj:1bci
PDBsum1bci
PubMed9665851
UniProtP47712|PA24A_HUMAN Cytosolic phospholipase A2 (Gene Name=PLA2G4A)

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