Structure of PDB 1b54 Chain A Binding Site BS01

Receptor Information
>1b54 Chain A (length=230) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GITYDEDRKTQLIAQYESVREVVNAEAKNVHSKILLLVVSKLKPASDIQI
LYDHGVREFGENYVQELIEKAKLLPDDIKWHFIGGLQTNKCKDLAKVPNL
YSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEA
EIFEVIDFFLSEECKYIKLNGLMTIGSWENRDFATLVEWKKKIDAKFGTS
LKLSMGMSADFREAIRQGTAEVRIGTDIFG
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain1b54 Chain A Residue 258 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1b54 Structure of a yeast hypothetical protein selected by a structural genomics approach.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		K49 N70 I91 M223 S224 R239 I240 G241 T242
Binding residue
(residue number reindexed from 1)		K41 N62 I83 M207 S208 R223 I224 G225 T226
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0042816 vitamin B6 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1b54, PDBe:1b54, PDBj:1b54
PDBsum1b54
PubMed12499548
UniProtP38197|PLPHP_YEAST Pyridoxal phosphate homeostasis protein (Gene Name=YBL036C)

[Back to BioLiP]