Structure of PDB 1b3t Chain A Binding Site BS01

Receptor Information
>1b3t Chain A (length=147) Species: 10376 (human gammaherpesvirus 4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGGWFGKHRGQGGSNPKFENIAEGLRALLARSHVERTTDEGTWVAGVFVY
GGSKTSLYNLRRGTALAIPQCRLTPLSRLPFGMAPGPGPQPGPLRESIVC
YFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSFDDGVDLP
Ligand information
Receptor-Ligand Complex Structure
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PDB1b3t The 2.2 A structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
K461 W464 F465 K467 R469 G470 G472 K514 Y518 R521 R522 P535 L536 R538
Binding residue
(residue number reindexed from 1)
K1 W4 F5 K7 R9 G10 G12 K54 Y58 R61 R62 P75 L76 R78
Enzymatic activity
Enzyme Commision number 3.1.21.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006275 regulation of DNA replication
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0042025 host cell nucleus

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Cellular Component
External links
PDB RCSB:1b3t, PDBe:1b3t, PDBj:1b3t
PDBsum1b3t
PubMed9878348
UniProtP03211|EBNA1_EBVB9 Epstein-Barr nuclear antigen 1 (Gene Name=EBNA1)

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