Structure of PDB 1b2v Chain A Binding Site BS01
Receptor Information
>1b2v Chain A (length=173) Species:
615
(Serratia marcescens) [
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AFSVNYDSSFGGYSIHDYLGQWASTFGDVNHTNGNVTDANSGGFYGGSLS
GSQYAISSTANQVTAFVAGGNLTYTLFNEPAHTLYGQLDSLSFGDGLSGG
DTSPYSIQVPDVSFGGLNLSSLQAQGHDGVVHQVVYGLMSGDTGALETAL
NGILDDYGLSVNSTFDQVAAATA
Ligand information
Ligand ID
HEM
InChI
InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;
InChIKey
KABFMIBPWCXCRK-RGGAHWMASA-L
SMILES
Software
SMILES
OpenEye OEToolkits 1.7.6
Cc1c2n3c(c1CCC(=O)O)C=C4C(=C(C5=[N]4[Fe]36[N]7=C(C=C8N6C(=C5)C(=C8C)C=C)C(=C(C7=C2)C)C=C)C)CCC(=O)O
CACTVS 3.385
CC1=C(CCC(O)=O)C2=Cc3n4[Fe]5|6|N2=C1C=c7n5c(=CC8=N|6C(=Cc4c(C)c3CCC(O)=O)C(=C8C=C)C)c(C)c7C=C
ACDLabs 12.01
C=1c3c(c(c4C=C5C(=C(C=6C=C7C(=C(C8=CC=2C(=C(C=1N=2[Fe](n34)(N5=6)N78)CCC(=O)O)C)\C=C)C)\C=C)C)C)CCC(=O)O
Formula
C34 H32 Fe N4 O4
Name
PROTOPORPHYRIN IX CONTAINING FE;
HEME
ChEMBL
DrugBank
DB18267
ZINC
PDB chain
1b2v Chain A Residue 200 [
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Receptor-Ligand Complex Structure
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PDB
1b2v
The crystal structure of HasA, a hemophore secreted by Serratia marcescens.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
H32 T33 N34 G35 V37 Y55 Y75 H83 Y137 M140
Binding residue
(residue number reindexed from 1)
H31 T32 N33 G34 V36 Y54 Y74 H82 Y136 M139
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005515
protein binding
GO:0046872
metal ion binding
Cellular Component
GO:0005576
extracellular region
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Molecular Function
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Cellular Component
External links
PDB
RCSB:1b2v
,
PDBe:1b2v
,
PDBj:1b2v
PDBsum
1b2v
PubMed
10360351
UniProt
Q54450
|HASA_SERMA Hemophore HasA (Gene Name=hasA)
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