Structure of PDB 1aya Chain A Binding Site BS01

Receptor Information
>1aya Chain A (length=101) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVT
HIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL
N
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1aya Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Resolution2.05 Å
Binding residue
(original residue number in PDB)
G13 R32 S34 K35 S36 T42 T52 H53 K55 G68 L88 K89 E90 K91
Binding residue
(residue number reindexed from 1)
G11 R30 S32 K33 S34 T40 T50 H51 K53 G66 L86 K87 E88 K89
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
External links
PDB RCSB:1aya, PDBe:1aya, PDBj:1aya
PDBsum1aya
PubMed7521735
UniProtP35235|PTN11_MOUSE Tyrosine-protein phosphatase non-receptor type 11 (Gene Name=Ptpn11)

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