Structure of PDB 1awc Chain A Binding Site BS01

Receptor Information
>1awc Chain A (length=110) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTM
NYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVI
ECEQKKLARM
Ligand information
Receptor-Ligand Complex Structure
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PDB1awc The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA.
Resolution2.15 Å
Binding residue
(original residue number in PDB)
Y371 R376 R379 Y380 Y382 K389 R394 F395
Binding residue
(residue number reindexed from 1)
Y52 R57 R60 Y61 Y63 K70 R75 F76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:1awc, PDBe:1awc, PDBj:1awc
PDBsum1awc
PubMed9461436
UniProtQ00422|GABPA_MOUSE GA-binding protein alpha chain (Gene Name=Gabpa)

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