Structure of PDB 1aqc Chain A Binding Site BS01
Receptor Information
>1aqc Chain A (length=130) Species:
9606
(Homo sapiens) [
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MEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLMT
EVDLFILTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRYKM
ICHVFESEDAQLIAQSIGQAFSVAYQEFLR
Ligand information
>1aqc Chain C (length=10) [
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GYENPTYKFF
Receptor-Ligand Complex Structure
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PDB
1aqc
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
R353 R414 I416 S417 Y418 I419 A420 R431 M458 A472 Q473 F479 Y483 F486
Binding residue
(residue number reindexed from 1)
R31 R78 I80 S81 Y82 I83 A84 R95 M100 A114 Q115 F121 Y125 F128
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1aqc
,
PDBe:1aqc
,
PDBj:1aqc
PDBsum
1aqc
PubMed
9321393
UniProt
Q02410
|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding family A member 1 (Gene Name=APBA1)
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