Structure of PDB 1anv Chain A Binding Site BS01

Receptor Information
>1anv Chain A (length=314) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAWEKGMEAARALMDKYHVDNDLKANFKLLPDQVEALAAVCKTWLNEEHR
GLQLTFTSNKTFVTMMGRFLQAYLQSFAEVTYKHHEPTGCALWLHRCAEI
EGELKCLHGSIMINKEHVIENVVQISNTDARCCVHDAACPANQFSGKSCG
MFFSEGAKAQVAFKQIKAFMQALYPNAQTGHGHLLMPLRCECNSKPGHAP
FLGRQLPKLTPFALSNAEDLDADLISDKSVLASVHHPALIVFQCCNPGGP
NCDFKISAPDLLNALVMVRSLWSENFTELPRMVVPEFKWSTKHQYRNVSL
PVAHSDARQNPFDF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1anv Chain A Residue 530 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1anv Conformational change of the adenovirus DNA-binding protein induced by soaking crystals with K3UO2F5 solutions.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		C284 H286 C339 C355
Binding residue
(residue number reindexed from 1)		C106 H108 C133 C149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006351 DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1anv, PDBe:1anv, PDBj:1anv
PDBsum1anv
PubMed15299602
UniProtP03265|DNB2_ADE05 DNA-binding protein (Gene Name=DBP)

[Back to BioLiP]