Structure of PDB 1agf Chain A Binding Site BS01
Receptor Information
>1agf Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1agf Chain C (length=8) Species:
11676
(Human immunodeficiency virus 1) [
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GGKKRYKL
Receptor-Ligand Complex Structure
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PDB
1agf
Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
Y7 D9 N63 I66 T69 N70 T73 D74 S77 Y84 S97 Y99 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 D9 N63 I66 T69 N70 T73 D74 S77 Y84 S97 Y99 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1agf
,
PDBe:1agf
,
PDBj:1agf
PDBsum
1agf
PubMed
8976183
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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