Structure of PDB 1agc Chain A Binding Site BS01

Receptor Information
>1agc Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIFKTNTQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1agc Chain C (length=8) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GGKKKYQL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1agc Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y7 D9 N63 N70 T73 D74 E76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 D9 N63 N70 T73 D74 E76 S77 N80 Y84 S97 Y99 Y116 Y123 T143 W147 V152 Q155 D156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1agc, PDBe:1agc, PDBj:1agc
PDBsum1agc
PubMed8976183
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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