Structure of PDB 1a6a Chain A Binding Site BS01

Receptor Information

>1a6a Chain A (length=176) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASF
EAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNV
LICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL
PSTEDVYDCRVEHWGLDEPLLKHWEF

Ligand information

>1a6a Chain C (length=15) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PVSKMRMATPLLMQA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1a6a The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
Resolution	2.75 Å
Binding residue (original residue number in PDB)	Q9 F24 A52 S53 F54 G58 N62 N69 I72
Binding residue (residue number reindexed from 1)	Q5 F20 A48 S49 F50 G54 N58 N65 I68

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:1a6a, PDBe:1a6a, PDBj:1a6a
PDBsum	1a6a
PubMed	7477400
UniProt	P01903\|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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