Structure of PDB 1a5v Chain A Binding Site BS01
Receptor Information
>1a5v Chain A (length=146) Species:
11889
(Rous sarcoma virus (strain Schmidt-Ruppin)) [
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GLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAAQH
HWATAIAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNSQGQ
AMVERANRLLKDKIRVLAEGDGFMKRIPTSKQGELLAKAMYALNHF
Ligand information
Ligand ID
MN
InChI
InChI=1S/Mn/q+2
InChIKey
WAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341
[Mn++]
Formula
Mn
Name
MANGANESE (II) ION
ChEMBL
DrugBank
DB06757
ZINC
PDB chain
1a5v Chain A Residue 2 [
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Receptor-Ligand Complex Structure
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PDB
1a5v
Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
D64 D121
Binding residue
(residue number reindexed from 1)
D11 D68
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4
: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
Biological Process
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:1a5v
,
PDBe:1a5v
,
PDBj:1a5v
PDBsum
1a5v
PubMed
9560188
UniProt
O92956
|POL_RSVSB Gag-Pol polyprotein (Gene Name=gag-pol)
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