Structure of PDB 1a5t Chain A Binding Site BS01
Receptor Information
>1a5t Chain A (length=324) Species:
83333
(Escherichia coli K-12) [
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MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLC
QQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNTLGVDAVREVTEKL
NEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPER
LLATLRSRCRLHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGA
ALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQAPARLHWLAT
LLMDALKRVTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGI
NRELLITDLLLRIEHYLQPGVVLP
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
1a5t Chain A Residue 501 [
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Receptor-Ligand Complex Structure
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PDB
1a5t
Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
C50 C62 C65
Binding residue
(residue number reindexed from 1)
C50 C62 C65
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.7.7
: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003689
DNA clamp loader activity
GO:0003887
DNA-directed DNA polymerase activity
GO:0005515
protein binding
GO:0008408
3'-5' exonuclease activity
Biological Process
GO:0006260
DNA replication
GO:0006261
DNA-templated DNA replication
GO:0071897
DNA biosynthetic process
Cellular Component
GO:0009360
DNA polymerase III complex
GO:0030894
replisome
GO:0043846
DNA polymerase III, clamp loader complex
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1a5t
,
PDBe:1a5t
,
PDBj:1a5t
PDBsum
1a5t
PubMed
9363942
UniProt
P28631
|HOLB_ECOLI DNA polymerase III subunit delta' (Gene Name=holB)
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