Structure of PDB 1a38 Chain A Binding Site BS01
Receptor Information
>1a38 Chain A (length=216) Species:
9913
(Bos taurus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKN
VVGARRSSWRVVSSIEQEKKQQMAREYREKIETELRDICNDVLSLLEKFL
IPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEI
SKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAESYK
DSTLIMQLLRDNLTLW
Ligand information
>1a38 Chain P (length=5) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
WLDLE
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1a38
14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
Resolution
3.35 Å
Binding residue
(original residue number in PDB)
K49 R60 K120 L220
Binding residue
(residue number reindexed from 1)
K49 R60 K115 L208
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0050815
phosphoserine residue binding
GO:0140311
protein sequestering activity
Biological Process
GO:0006468
protein phosphorylation
GO:0007165
signal transduction
GO:0008104
protein localization
GO:0070372
regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005737
cytoplasm
GO:0042470
melanosome
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1a38
,
PDBe:1a38
,
PDBj:1a38
PDBsum
1a38
PubMed
9632691
UniProt
P63103
|1433Z_BOVIN 14-3-3 protein zeta/delta (Gene Name=YWHAZ)
[
Back to BioLiP
]