Structure of PDB 1a2x Chain A Binding Site BS01
Receptor Information
>1a2x Chain A (length=158) Species:
9986
(Oryctolagus cuniculus) [
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DQQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPT
KEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRI
FDRNADGYIDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEF
LKMMEGVQ
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
1a2x Chain A Residue 160 [
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Receptor-Ligand Complex Structure
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PDB
1a2x
Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
D103 N105 D107 Y109 E114
Binding residue
(residue number reindexed from 1)
D102 N104 D106 Y108 E113
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
V42
Catalytic site (residue number reindexed from 1)
V41
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005509
calcium ion binding
GO:0031014
troponin T binding
GO:0046872
metal ion binding
Cellular Component
GO:0016460
myosin II complex
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Molecular Function
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Cellular Component
External links
PDB
RCSB:1a2x
,
PDBe:1a2x
,
PDBj:1a2x
PDBsum
1a2x
PubMed
9560191
UniProt
P02586
|TNNC2_RABIT Troponin C, skeletal muscle (Gene Name=TNNC2)
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