Structure of PDB 1a1o Chain A Binding Site BS01

Receptor Information
>1a1o Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRPP
WIEQEGPEYWDRNTQIFKTNTQTYRENLRIALRYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1a1o Chain C (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KPIVQYDNF
Receptor-Ligand Complex Structure
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PDB1a1o Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y7 R62 N63 I66 T69 N77 I80 Y84 R97 Y99 Y123 T143 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 R62 N63 I66 T69 N77 I80 Y84 R97 Y99 Y123 T143 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1a1o, PDBe:1a1o, PDBj:1a1o
PDBsum1a1o
PubMed8624812
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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