Structure of PDB 1a1m Chain A Binding Site BS01

Receptor Information
>1a1m Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRPP
WIEQEGPEYWDRNTQIFKTNTQTYRENLRIALRYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPHH
Ligand information
>1a1m Chain C (length=9) Species: 11709 (Human immunodeficiency virus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TPYDINQML
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1a1m Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y7 Y9 N63 Y74 N77 Y84 R97 Y99 D114 Y123 T143 K146 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Y9 N63 Y74 N77 Y84 R97 Y99 D114 Y123 T143 K146 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1a1m, PDBe:1a1m, PDBj:1a1m
PDBsum1a1m
PubMed8624812
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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