Structure of PDB 1a1a Chain A Binding Site BS01
Receptor Information
>1a1a Chain A (length=106) Species:
9606
(Homo sapiens) [
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DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYSLSVSD
FDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCP
Ligand information
>1a1a Chain C (length=3) [
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YEc
Receptor-Ligand Complex Structure
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PDB
1a1a
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
R158 R178 S180 E181 T182 S188 H204 Y205 K206 G239
Binding residue
(residue number reindexed from 1)
R15 R35 S37 E38 T39 S45 H61 Y62 K63 G96
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1a1a
,
PDBe:1a1a
,
PDBj:1a1a
PDBsum
1a1a
PubMed
9174343
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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