Structure of PDB 1a08 Chain A Binding Site BS01
Receptor Information
>1a08 Chain A (length=105) Species:
9606
(Homo sapiens) [
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SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF
DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRL
TTVCP
Ligand information
>1a08 Chain C (length=3) [
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YEc
Receptor-Ligand Complex Structure
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PDB
1a08
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
R158 R178 S180 C188 K203 H204 Y205 K206
Binding residue
(residue number reindexed from 1)
R14 R34 S36 C44 K59 H60 Y61 K62
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1a08
,
PDBe:1a08
,
PDBj:1a08
PDBsum
1a08
PubMed
9174343
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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