Structure of PDB 182l Chain A Binding Site BS01
Receptor Information
>182l Chain A (length=162) Species:
10665
(Tequatrovirus T4) [
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MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI
GRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAAAI
NMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVI
TTFRTGTWDAYK
Ligand information
Ligand ID
BZF
InChI
InChI=1S/C8H6O/c1-2-4-8-7(3-1)5-6-9-8/h1-6H
InChIKey
IANQTJSKSUMEQM-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
o1ccc2ccccc12
OpenEye OEToolkits 1.5.0
c1ccc2c(c1)cco2
ACDLabs 10.04
o2c1ccccc1cc2
Formula
C8 H6 O
Name
BENZOFURAN
ChEMBL
CHEMBL363614
DrugBank
DB04179
ZINC
ZINC000001591814
PDB chain
182l Chain A Residue 401 [
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Receptor-Ligand Complex Structure
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PDB
182l
Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
L84 V87 A99 M102 V111 L118
Binding residue
(residue number reindexed from 1)
L84 V87 A99 M102 V111 L118
Annotation score
1
Binding affinity
MOAD
: Ka=8900M^-1
Enzymatic activity
Catalytic site (original residue number in PDB)
E11 D20
Catalytic site (residue number reindexed from 1)
E11 D20
Enzyme Commision number
3.2.1.17
: lysozyme.
Gene Ontology
Molecular Function
GO:0003796
lysozyme activity
GO:0016798
hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253
peptidoglycan catabolic process
GO:0016998
cell wall macromolecule catabolic process
GO:0031640
killing of cells of another organism
GO:0042742
defense response to bacterium
GO:0044659
viral release from host cell by cytolysis
Cellular Component
GO:0030430
host cell cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:182l
,
PDBe:182l
,
PDBj:182l
PDBsum
182l
PubMed
7612599
UniProt
P00720
|ENLYS_BPT4 Endolysin (Gene Name=E)
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