Structure of PDB 4wu1 Chain 9I Binding Site BS01

Receptor Information
>4wu1 Chain 9I (length=72) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRIL
AKTIKRARILGLLPFTEKLVRK
Ligand information
>4wu1 Chain 13 (length=1501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaaga
caugcaagucgugcgggccgcgggcuccguggucagcggcggacggguga
guaacgcgugggugaccuacccggaagagggggacaacccggggaaacuc
gggcuaaucccccauguggacccgccccuugggguguguccaaagggcuu
ugcccgcuuccggaugggcccgcgucccaucagcuaguuggugggguaau
ggcccaccaaggcgacgacggguagccggucugagaggauggccggccac
aggggcacugagacacgggccccacuccuacgggaggcagcaguuaggaa
ucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggaggaaga
agcccuucgggguguaaacuccugaacccgggacgaaacccccgacgagg
ggacugacgguaccgggguaauagcgccggccaacuccgugccagcagcc
gcgguaauacggagggcgcgagcguuacccggauucacugggcguaaagg
gcguguaggcggccuggggcgucccaugugaaagaccacggcucaaccgu
gggggagcgugggauacgcucaggcuagacggugggagagggugguggaa
uucccggaguagcggugaaaugcgcagauaccgggaggaacgccgauggc
gaaggcagccaccugguccacccgugacgcugaggcgcgaaagcgugggg
agcaaaccggauuagauacccggguaguccacgcccuaaacgaugcgcgc
uaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgccgc
cuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggccc
gcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccuu
accaggccuugacaugcuagggaacccgggugaaagccuggggugccccg
cgaggggagcccuagcacaggugcugcauggccgucgucagcucgugccg
ugagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguug
ccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggagg
aaggaggggacgacgucuggucagcauggcccuuacggccugggcgacac
acgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagcu
aaucgcaaaaaggugggcccaguucggauuggggucugcaacccgacccc
augaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaaua
cguucccgggccuuguacacaccgcccgucacgccaugggagcgggcucu
acccgaagucgccgggagccuacgggcaggcgccgaggguagggcccgug
acuggggcgaagucguaacaagguagcuguaccggaaggugcggcuggau
c
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<
<.<<<..<<<..<<.<<<<<<<.....>>>>>>>.>>>>>......<<..
.....<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>
>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<<<<..
.>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.....
..>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>
.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>>....
....<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<.....
.<<<<....>>>>.....>>>>....<<<<<........<<<<.....>>
>>..........>>>>>......<<<<<(((...<<<<<.....<<.)))
>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....
<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>
>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....
<<<<<<<.<..<<<......>>>.....>.>>>>>>>...........<<
....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<..
.<<...<<<<.........>>>>...>>>>>>>>..........<<<<<<
..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>
>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<
<.<<.<<<<<<..<<<<<<<<<<......<<........>>.........
.<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>...<<<..
....>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.
...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...
<...<<<.....>>>>.....>>>>>>>.....<<<<<....>>>>>...
.....>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>
>>>>>>>.....<<<<<<<.....<<<..<.<.<<<<....>>>>..>>.
...>>>.....>>>>>>>...........<<<<<<<........>>>>>>
>..........>>>>>>....<<<<<<<..........>>>>>>>.....
.>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<
<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>.
.>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>....
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4wu1 Structural insights into the translational infidelity mechanism.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K49 I50 R53 K61 R64 K68 K71 R72 R74 I75 F81
Binding residue
(residue number reindexed from 1)		K33 I34 R37 K45 R48 K52 K55 R56 R58 I59 F65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4wu1, PDBe:4wu1, PDBj:4wu1
PDBsum4wu1
PubMed26037619
UniProtQ5SLQ0|RS18_THET8 Small ribosomal subunit protein bS18 (Gene Name=rpsR)

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