Structure of PDB 8fnk Chain 9 Binding Site BS01

Receptor Information
>8fnk Chain 9 (length=858) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLLPTLERLLERCGRPIFSNVEDVRMVMASLLDISAYVDRASTKVIAKPL
RRFCHKDPDTVASVMEAVPIDAAEPTHGRRAAMLLRCLPKHSCDEVIWER
AVAATLAGLKSRKWDLHDYRVAMAHAGRGGRHAPALAAAAEEFVSSSART
ASQSELPALLVILTSLPELKRSPCLQVAADRIVQLSEILSPAAIGQICAS
VNKVSFRHTAMAIALQEEAIRFAEESDLFSAVQLFSFICQQEKEAISPDA
VKCLAERVIEGKDLDQETVSVLCRALRSIPRPHRPELLREIGEMMEFLGG
EVKELLELPVAKGGLKGDVSAGDIQSFISKFLSLDGLLPADHDRPGTYMA
AIVACVDYITERLEDIVSDENPPFSIIPHLLNINMEETRRCGQAIIREAA
EQGIHFPTLQVFRFLLALGDHNMRDQRVYRHLRNEFAKTASDIPMIQLCA
ALKCFVRGLMQNVETQSLDEQVEHELEKEDMDAFLRFCVENLRRGFADGM
EVKCVMAATESLYQLGYTSTEFYEQVARYLGSKCSSASASVNSSETATAV
CLALGEDILDRHPDVHTFLLEVEKSGLKGEASLSPTEWMNKNDPANFITP
LTEIQQEGWNIINRMVETRAADTEKLTALANEYVAILKSTRVDDLKYFFG
VFEEKVFKQDRILKQCLDYLVESNAAVKLSATSIGAMLNSLAAIRFTYHR
SVKQFMIAISTEQWSEMDASPLVKIVSAMAKLSLRLPQVLVHVGDRLLDV
YTFLSPLDTALVINSLQSIGYGNDEVLMMLMRHAASSARRWDEVSLTLLF
GASGVHRLLRNVEVAAPLLEQAAGKTSSPHLRQRIAASLRRSALPRALVQ
SSTSLLTG
Ligand information
>8fnk Chain m (length=51) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB8fnk Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		S720 K724 K731 D758 L798 G801 R834
Binding residue
(residue number reindexed from 1)		S720 K724 K731 D758 L798 G801 R834
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0016554 cytidine to uridine editing
GO:0048255 mRNA stabilization
GO:0090615 mitochondrial mRNA processing
Cellular Component
GO:0005739 mitochondrion
GO:0020023 kinetoplast
GO:0031019 mitochondrial mRNA editing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fnk, PDBe:8fnk, PDBj:8fnk
PDBsum8fnk
PubMed37410820
UniProtQ585T1

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