Structure of PDB 7zeb Chain 9 Binding Site BS01

Receptor Information
>7zeb Chain 9 (length=171) Species: 9940 (Ovis aries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYKYVNLRMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINYPFEKG
PLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRADGSRR
TTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLL
NNGDKWEAEIAANIQADYLYR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7zeb Chain 9 Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zeb A universal coupling mechanism of respiratory complex I.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		H65 C87 P88 I92 C116 I117 Y118 C119 G120 C122
Binding residue
(residue number reindexed from 1)		H60 C82 P83 I87 C111 I112 Y113 C114 G115 C117
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zeb, PDBe:7zeb, PDBj:7zeb
PDBsum7zeb
PubMed36104567
UniProtA0A6P3TFB2

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