Structure of PDB 7zdm Chain 9 Binding Site BS01

Receptor Information

>7zdm Chain 9 (length=176) Species: 9940 (Ovis aries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TYKYVNLREPSMDMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINY
PFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRA
DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYN
KEKLLNNGDKWEAEIAANIQADYLYR

Ligand information

InChI=1S/4Fe.4S

LJBDFODJNLIPKO-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.7	[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385	S1[Fe]S[Fe]1.S2[Fe]S[Fe]2

Formula

Fe4 S4

Name

IRON/SULFUR CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

7zdm Chain 9 Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7zdm A universal coupling mechanism of respiratory complex I.
Resolution	3.44 Å
Binding residue (original residue number in PDB)	H65 C87 P88 I92 C116 I117 Y118 C119 G120 F121 C122
Binding residue (residue number reindexed from 1)	H65 C87 P88 I92 C116 I117 Y118 C119 G120 F121 C122
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003954	NADH dehydrogenase activity
GO:0016651	oxidoreductase activity, acting on NAD(P)H
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:0006120	mitochondrial electron transport, NADH to ubiquinone
GO:0032981	mitochondrial respiratory chain complex I assembly

	Cellular Component
GO:0005739	mitochondrion
GO:0016020	membrane

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External links

PDB	RCSB:7zdm, PDBe:7zdm, PDBj:7zdm
PDBsum	7zdm
PubMed	36104567
UniProt	A0A6P3TFB2

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