Structure of PDB 7of5 Chain 9 Binding Site BS01

Receptor Information
>7of5 Chain 9 (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADRMSKWTSKRGPRSFRGRKGRGAKGIGFLTSGWRFVQIKEMVPEFVVPD
LTGFKLKPYVSYLAPESEETPLTAAQLFSEAVAPAIEKDFKDNLEKYGFE
PTQEGKLFQLYPRNFLR
Ligand information
>7of5 Chain A (length=1389) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccaaaccuuagccaaacca
uuuacauaaaguauaggcgauagaaauugauggcgcaauagauauaguac
cgcaagggaaagaugaaaaacaagcauaauauagcaaggacuaaccccua
uaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagagccaa
agcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaagagc
acacccgucuauguagcaaaauagugggaagauuuauagguagaggcgac
aaaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguu
caacuuuaaauuugcccacagaacccaaauccccuuguaaauuuaacugu
uaguccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagag
agaguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauua
agaaagcguucaagcucaacacaaaaaucccaaacauauaacugaacucc
ucacacccaauuggaccaaucuaucacccuauagaagaacuaauguuagu
auaaguaacaugaaaacauucuccuccgcauaagccugcgucagcugaca
auuaacagcccaauaucuacaaucaaccaacaagucauuauuacccucac
ugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaa
ggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuag
caucaccaguauuagaggcaccgccuuccuuaaauagggauggcuccacg
aggguucagcugucucuuacuuuuaaccagugaaauugaccugcccguga
agaggcgggcauaacacagcaagacgagaagacccuauggagcuuuaauu
uauuaaugcaaacaccugcauuaaaaauuucgguuggggcgaccucggag
cagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaagcg
aaccucaauugauccaauaacuugaccaacggaacaaguuacccuaggga
uaacagcgcaauccuauucuagaguccauaucaacaauaggguuuacgac
cucgauguuggaucaggacaucccgauggugcagccgcuauuaaagguuc
guuuguucaacgauuaaaguccuacgugaucugaguucagaccggaguaa
uccaggucgguuucuaucuacuuuaauuccucccuguacgaaaggacaag
agaaauaaggccuacuucacaaagcgccuucccccguaaaugauaucauc
ucaacuuaguauuauacccacacacccaagaacaggguu
<<<.......<<<<..............................<.....
.>...........<<.....>>.........>>.>>.............<
<....>>...............>>>...........<<<.......>>>.
..<.<........>.>.<<<<<<.........<<<.<<..<<....>>..
.>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>
...<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<....
...>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>
><<<.<<<<<<<<<<.....<<.......>>.....>>>>>>>>>>..>>
>.<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<
.<<<...<..............<....<<<.........>>>....>...
....<<<......>>>..........................>...>>>>
>>........>>>>>>...<<<<<......>>>>>.........>>>>>>
.......<<..<<<....>>><<<<..<<<<........<<<<..>>>>.
.....<<<...<<<<.......................>>>>.......>
>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<
<.........<......<<<<<<..<<<.........>>>...<<<<<<.
............>>>>>>....<<<.<<<<.....>>>>..>>>....>>
.>>>>.....>..>>.>>>>>>>>>>>>.>>...........<<<<<...
.....>>>>>.......<<..<<<.<<......<<<<.<<<<<<..<<<<
<.<<<<<<<<......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<
...........>>>>>>..<<.....<<<..<<<<.....>>>>..>>>.
...>>.........<<<....>>>............>>>>..>>>>>>..
.....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>
......<<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<
<<<.....>>>>>.....>>>>>..>...>>>.>>>...<<<<<<<....
>>>.>>>>....>>..>>>.>>...<<<.<<<.................>
>>.>>><<<<<...<<<....>>>.>>>>>......<<<...........
.....>>>...............<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of5 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D16 R17 M18 W21 S23 K24 R25 P27 R28 S29 F30 R31 G32 R33 K34 K39 G40 L44 T45 S46 G47 W48 F50 V51 Q52
Binding residue
(residue number reindexed from 1)		D2 R3 M4 W7 S9 K10 R11 P13 R14 S15 F16 R17 G18 R19 K20 K25 G26 L30 T31 S32 G33 W34 F36 V37 Q38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0006915 apoptotic process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of5, PDBe:7of5, PDBj:7of5
PDBsum7of5
PubMed34135319
UniProtQ8IXM3|RM41_HUMAN Large ribosomal subunit protein mL41 (Gene Name=MRPL41)

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