Structure of PDB 7odt Chain 9 Binding Site BS01

Receptor Information
>7odt Chain 9 (length=124) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GADRMSKWTSKRGPRSFRGRKGRGAKGIGFLTSGWRFVQIKEMVPEFVVP
DLTGFKLKPYVSYLAPESEETPLTAAQLFSEAVAPAIEKDFKDGTFDPDN
LEKYGFEPTQEGKLFQLYPRNFLR
Ligand information
>7odt Chain A (length=1453) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaa
aaaucccaaacauauaacugaacuccucacacccaauuggaccaaucuau
cacccuauagaagaacuaauguuaguauaaguaacaugaaaacauucucc
uccgcauaagccugcgucagauuaaaacacugaacugacaauuaacagcc
caauaucuacaaucaaccaacaagucauuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccugcaaucacuuguuccuuaaauagggaccuguauu
ggcuccacgaggguucagcugucucuuacuuuuaaccagugaaauugacc
ugcccgugaagaggcgggcauaacacagcaagacgagaagacccuaugga
gcuuuaauuuauuaaugcaaacagaaaccugcauuaaaaauuucgguugg
ggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuuc
accagucaaagcgaacacucaauugauccaauaacuugaccaacggaaca
aguuacccuagggauaacagcgcaauccuauucuagaguccauaucaaca
auaggguuuacgaccucgauguuggaucaggacaucccgauggugcagcc
gcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugagu
ucagaccggaguaauccaggucgguuucuaucuacuuucaaauuccuccc
uguacgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccc
cguaaaugauaucaucucaacuuaguauacccaccccacccaagaacagg
guu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
..................>...>>>>>>........>>>>>>...<<<<<
......>>>>>.........>>>>>><......<<..<<<....>>><<<
<..<<<<........<<<<<..............>>>>>......<<<..
.<<<<.......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
.......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<.......<<..<<<<<<.....>>>>>>..>>...
>>>....>>.>>>>........>>.>>>>>>>>>>>>.>>.....>....
.<<<<<........>>>>>.......<<..<<<.<<......<<<<.<<<
<<<..<<<<<.<<<<<<<<..........>>>>>>>>>>>>>..<<<<..
...>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<..
...>>>>..>>>.....>>.........<<<....>>>............
>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>
>>>>>...>.>>.>......<<<<<<.<<<<<<..<<.<<<<<<......
>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>>
...<<<<<<<....>>>.>>>>....>>..>>>.>>...<.<<<.<<<..
...............>>>.>>><<<<<...<<<....>>>.>>>>>....
..<<<................>>>...>.........<<<<.......>>
>>.
Receptor-Ligand Complex Structure
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PDB7odt Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		D16 R17 M18 W21 S23 K24 P27 R28 F30 R31 G32 R33 K34 K39 G40 I41 L44 T45 G47 W48 R49 F50 V51 Q52
Binding residue
(residue number reindexed from 1)		D3 R4 M5 W8 S10 K11 P14 R15 F17 R18 G19 R20 K21 K26 G27 I28 L31 T32 G34 W35 R36 F37 V38 Q39
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0006915 apoptotic process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7odt, PDBe:7odt, PDBj:7odt
PDBsum7odt
PubMed34135320
UniProtQ8IXM3|RM41_HUMAN Large ribosomal subunit protein mL41 (Gene Name=MRPL41)

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