Structure of PDB 4csu Chain 9 Binding Site BS01

Receptor Information
>4csu Chain 9 (length=333) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENL
NTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGE
TMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELL
LELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRM
DNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGT
DPVENARIIISELEKYSQDLATKPRWLVFNKIDLLDKVEAEEKAKAIAEA
LGWEDKYYLISAASGLGVKDLCWDVMTFIIENP
Ligand information
>4csu Chain A (length=115) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcugcggccguagcgcgguggucccaccugaccccaugccgaacucagaa
gugaaacgccguagcgccgaugguaguguggggucuccccaugcgagagu
agggaacugccaggc
.<<<<<<.....<<<<<<<<....<<<<<<<.............>>>>..
>>>...>>>>>>.>>.<<.....<.<<<<<<<<...>>>>>>>>...>..
.>>...>>>>.>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4csu Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Resolution5.5 Å
Binding residue
(original residue number in PDB)		D107 P336
Binding residue
(residue number reindexed from 1)		D104 P333
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0019003 GDP binding
GO:0019843 rRNA binding
GO:0032561 guanyl ribonucleotide binding
GO:0043023 ribosomal large subunit binding
GO:0046872 metal ion binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0007059 chromosome segregation
GO:0022611 dormancy process
GO:0042254 ribosome biogenesis
GO:0042255 ribosome assembly
GO:0090071 negative regulation of ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4csu, PDBe:4csu, PDBj:4csu
PDBsum4csu
PubMed24844575
UniProtP42641|OBG_ECOLI GTPase ObgE/CgtA (Gene Name=obgE)

[Back to BioLiP]