Structure of PDB 2w49 Chain 9 Binding Site BS01

Receptor Information
>2w49 Chain 9 (length=159) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNP
TKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFR
IFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDE
FLKMMEGVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2w49 Chain 9 Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2w49 Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Resolution35.0 Å
Binding residue
(original residue number in PDB)		D105 N107 D109 F111 I112 E116
Binding residue
(residue number reindexed from 1)		D103 N105 D107 F109 I110 E114
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0003009 skeletal muscle contraction
Cellular Component
GO:0005861 troponin complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2w49, PDBe:2w49, PDBj:2w49
PDBsum2w49
PubMed20844746
UniProtP02588|TNNC2_CHICK Troponin C, skeletal muscle (Gene Name=TNNC2)

[Back to BioLiP]