Structure of PDB 8csp Chain 8 Binding Site BS01

Receptor Information
>8csp Chain 8 (length=326) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLEL
SLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVG
EFAALVFAGAMEFAEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFN
FACLEAREHCKSLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKF
HFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSNVHAHR
YRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLG
AILKSCNMQAWKSYSAVDVLQTLEHV
Ligand information
>8csp Chain A (length=737) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucaaauaaagcuaaaaaaauagacuacgaaaguggcuuuaacauau
cugaacacacaauagcuaagacccaaacugggauuagauaccccacuaug
cuuagcaacaguuaaaucaacaaaacugcucgccagaacacuacgagcca
cagcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggag
ccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucag
ccuauauaccgccaucuuaacccugaugaaggcuacaaaguacguuaggu
caagguguagcccaugagguggcaagaaaugggcuacauuuucuacccca
gaaaauuuagcaguaaacugagaggcuuaguugaacagggcccugaagcg
cgucgucaagucguaaaguguacuggaaagugcacuu
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<.....<<<<<<..............<<....>>.>>>>>>.....>
>>>...>>>>....<<<<<<...<<...<<<<.........>>>>...>>
>>>>>><.<<<<<......))..>>>>>.>.>>>.<<....<..<<<<..
..>>>>...>.>>..>>>>>>.....<<<<<<<<...<<<.<<<<<..<<
<<<<<<<<......<<................>>.<<<<<<<.......<
<.<<<..<<<<<<<.<...<<<<<.....>>>.......>>..>.>.>>>
...>>>>>>>>....>>>>>>>..>>>>.>>>>>>.....<<<<.....>
>>>..>>>>>.....<<<<<<<...>>>>>>>.....>>>...>>>>>>>
>..<<......>>..<<<<<<<<<....>>>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8csp Principles of mitoribosomal small subunit assembly in eukaryotes.
Resolution2.66 Å
Binding residue
(original residue number in PDB)		R56 R57 P59 C62 V147 P200 P233 R236 R305 R307 H308 E327 Q328 H331 A332 I333 Y334 E335 R336 K338 N362 M363 K367
Binding residue
(residue number reindexed from 1)		R1 R2 P4 C7 V92 P145 P178 R181 R250 R252 H253 E272 Q273 H276 A277 I278 Y279 E280 R281 K283 N307 M308 K312
Enzymatic activity
Enzyme Commision number 2.3.1.39: [acyl-carrier-protein] S-malonyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006635 fatty acid beta-oxidation
GO:0032787 monocarboxylic acid metabolic process
GO:0180026 mitochondrial small ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8csp, PDBe:8csp, PDBj:8csp
PDBsum8csp
PubMed36482135
UniProtQ8IVS2|FABD_HUMAN Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (Gene Name=MCAT)

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