Structure of PDB 7r72 Chain 8 Binding Site BS01

Receptor Information
>7r72 Chain 8 (length=58) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVSKSTKKFQSKHLKHTLDQRRKEKIQKKRIQGRRGNKTDQEKADAAGTR
EQQQLKKS
Ligand information
>7r72 Chain 1 (length=641) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augccugaauagggugaagccagaggaaacucugguggaggcucgcgaau
uuggguauaguagcaaauauucaaaugagaacuuugaagacugaaguggg
gaaagguuccacgucaacagcaguuggacguggguuagucgauccuaaga
gaugguuucaaaggccugauucaggccaccaucgaaagggaauccgguua
agauuccggaaccuggauauggauucuucacgguaacguaacugaaugug
gagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcu
uaucaccccggaauugguuuauccggagauggggucuuauggcuggaaga
ggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauc
cacaggaaggaauaguuuucaugccaggucguacugucuccaaggugaac
agccucuaguugauagaauccguaacuucgggauaaggauuggcucuaag
ggucggguagugagggccuuggucacggccuuggcuugcuacaauuaacg
aucaacuuagaacugguacggacaauaucuagcgaggcugucugaucagg
cauugcguaagcaguagaguagccguuacgaucugcugaga
<<<<<<<<...<<<....<<<<<<<....>>>>>>>.....>>>......
>>>>>>>>....<<.....<<<<<<.......>>>>>><<<<.....<<<
<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<
............<<<<<<...>>>>>>....>>....>>...<<<<<...
.....>>>>>))<<<<.<<<<<<......<<<....>>>.......<<<<
<<...<<<<.<<<<<<<.<<<<<<<<<<..(((..>>>>>><...<<<<<
....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....>
<<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>
>>>>............>>.>>>>>>>>>>>>..>>.>>>>>.<<<<....
.>>>>..>>>>..<<<<.<<<<<<.<<<<.....................
<<<<<.<<<<<<<<..<<..<<<<..>>>>..>>>>>>>>>>......>>
>>>......>>>...>>>>>>>.....>>>>>>...<<<<<<<))).>>>
>>..>>....<<<<....<<.......>>...>>>>.....
Receptor-Ligand Complex Structure
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PDB7r72 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.07 Å
Binding residue
(original residue number in PDB)
K3 S5 K6 S7 T8 K9 K10 F11 Q12 H15 H18 L20 Q22 R23 E26 Q29 R36 G38 N39
Binding residue
(residue number reindexed from 1)
K1 S3 K4 S5 T6 K7 K8 F9 Q10 H13 H16 L18 Q20 R21 E24 Q27 R34 G36 N37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030687 preribosome, large subunit precursor
GO:0030690 Noc1p-Noc2p complex
GO:0030691 Noc2p-Noc3p complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7r72, PDBe:7r72, PDBj:7r72
PDBsum7r72
PubMed36482249
UniProtP39744|NOC2_YEAST Nucleolar complex protein 2 (Gene Name=NOC2)

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