Structure of PDB 7p7s Chain 8 Binding Site BS01

Receptor Information
>7p7s Chain 8 (length=38) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG
Ligand information
>7p7s Chain A (length=2901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaagugaauaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacuaacaccgauaugcuuuggggagcuguaaguaagcuauga
uccagagauuuccgaaugggggaacccaauaucuuuuauaggauauuacu
uuucagugaauacauagcugauuagagguagacgcagagaacugaaacau
cuuaguaccugcaggaagagaaagaaaauucgauucccugaguagcggcg
agcgaaacgggaagagcccaaaccaacaagcuuguugggguuguaggacu
ccgauaugguagucuguuaguauaguugaaggauuuggaaaauuccgcua
aagagggugaaagccccguagacgaaaugcugacaacaccuaggaggauc
cugaguacggcggaacacgagaaauuccgucggaauccgcggggaccauc
ccgcaaggcuaaauacucccuagugaccgauagugaaccaguaccgugag
ggaaaggugaaaagcaccccggaaggggagugaaauagauccugaaaccg
ugugccuacaacaagucaaagcucguuaaugagugauggcgugccuuuug
uagaaugaaccggcgaguuacgauugcaugcgagguuaagucgaagagac
ggagccgcagcgaaagcgagucugaauagggcgaaugaguauguagucgu
agacccgaaaccaugugaucuacccauguccagguugaaggugcgguaaa
acgcacuggaggaccgaacccacguacguugaaaagugcggggaugaggu
guggguagcggagaaauuccaaacgaacuuggagauagcugguucucucc
gaaauagcuuuagggcuagccucggaauugagaaugauggagguagagca
cuguuuggacuaggggcccaucucggguuaccgaauucagauaaacuccg
aaugccauucauuuauauccgggagucagacugcgagugauaagauccgu
agucgaaagggaaacagcccagaccaccagcuaaggucccaaaauauaug
uuaaguggaaaaggaugugggguugcacagacaacuaggauguuggcuua
gaagcagccaccauuuaaagagugcguaauagcucacuagucgagugacc
cugcgccgaaaauguaccggggcuaaacauauuaccgaagcuguggacua
caccauuagguguagugguaggagagcguucuaagggcguugaaggucga
ucgugaggacggcuggagcgcuuagaagugagaaugccgguaugaguagc
gaaagacaggugagaauccuguccaccguaugacuaagguuuccugggga
aggcucguccgcccaggguuagucgggaccuaagccgaggccgauaggcg
uaggcgauggacaacagguugauauuccuguaccaguuguuuuuguuuga
gcaauggagggacgcaguaggcuaaggaaugcaugcgauuggaagugcau
guccaagcaaugagucuugaguagaguuaaaugcuuuacucuuuaaggac
aaguugugacggggagcgaaauaguagcgaaguuccugacgucacacugc
caagaaaagcuucuagugagaaaacaacugcccguaccguaaaccgacac
agguagucgaggagaguauccuaaggugagcgagcgaacucucguuaagg
aacucggcaaaaugaccccguaacuucgggagaaggggugcugacuucgg
ucagccgcagugaauaggcccaagcgacuguuuaucaaaaacacaggucu
cugcaaaaucguaagaugaaguauaggggcugacgccugcccggugcugg
aagguuaagaggauggguuagcuucggcgaagcucagaauugaagcccca
guaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugu
cggguaaguuccgacccgcacgaaaggcguaacgauuugggcacugucuc
aacgagagacucggugaaauuuuaguaccugugaagaugcagguuacccg
cgacaggacggaaagaccccauggagcuuuacuguaguuugauauugagu
guuuguaccacauguacaggauagguaggagccgaugagaccggaacgcu
aguuucggaggaggcgcuggugggauacuacccuuguguuaugaacccuc
uaacccgcaccacuaaucguggugggagacagugucagaugggcaguuug
acuggggcggucgccuccuaaaagguaacggaggcgcccaaagguucccu
cagaaugguuggaaaucauucgaagaguguaaaggcagaagggagcuuga
cugcgagaccuacaagucgagcagggacgaaagucgggcuuagugauccg
gugguuccgcauggaagggccaucgcucaacggauaaaagcuacccuggg
gauaacaggcuuaucucccccaagaguccacaucgacggggagguuuggc
accucgaugucggcucgucgcauccuggggcuguagucggucccaagggu
ugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgu
gagacaguucggucccuauccgucgcgggcguuggaaauuugagaggagc
uguccuuaguacgagaggaccgggauggacuuaccgcugguguaccaguu
guucugccaagggcauugcuggguagcuauguagggaagggauaaacgcu
gaaagcaucuaagugugaagcccaccucaagaugagauuucccauuucuu
uaagaaaguaagaccccugagagaugaucagguagauagguuggaagugg
aaggcuagugauaguuggagcggaccaauacuaaucggucgaggacuuaa
c
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<<.....<<<.<<.<<<<<<<<<.<<<...<<<.<......>.>>>((..
....<<<.....))>>>...>>>...>>>>>>>>>>>>>>..>>>>..>>
>>.....<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>
>>>>..)))......]].>>>>>>>.]]...............<<....>
>....]].........<<<<....>>>>..................>>>>
>>>>>>>.......<<<<..<<<<......>>>>..>>>>...<.<....
....>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<.....>>>
...>>>...<<....>>..<<<<.....>>>>......>>>>>>>>>>>>
>..<<.<...<<<.<<.....<<<<<<<<<..<<<....<<<<<<.....
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>>>>>>...<<<.....>>>......>>.>>>......>.>>..<<<<<<
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.<<.<<<<<...<<<<<<<.....>>>>>.>>...>>>>>.>>..>>.>.
....>>>>.>>>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>
>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<
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<<....>>.>>>>>...>>.>>>>>>>........>>>>>><......<<
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>><<..<<<<<..<<<<.<<<<<<<<<.....>>>>>>>>>.....>>>>
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.........>>>>..>>..>>>>>>>>>>>>>>>.>>>.....<<.....
.>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.
..............<<<<<...............>>>>><<<<<<....>
>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<
<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<
..<<<...<<...<<<<<..<<....>>...>>>>>...>>...>>>>>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.
>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<
<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<.
<<<<<<<.<<<<...........<<<<<..<<<.......<<<<<<<...
.>>>>>>>....>>>............>>>>>..>>>>.>>>>>>>.>>>
....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<
<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>...
<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<<
<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>
.......<<<<...<<<<<<...<<.......>>...>>>>>>....>>>
.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.
<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<
<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<
<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<<<
...........>>>>>....>>>.>>>>.......>>>>>>>..<<<<..
...>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<..
..<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p7s Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
M1 K2 R4 P5 S6 V7 K8 M10 R19 K20 R22 P31 K32 K34 R36 Q37 G38
Binding residue
(residue number reindexed from 1)
M1 K2 R4 P5 S6 V7 K8 M10 R19 K20 R22 P31 K32 K34 R36 Q37 G38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7p7s, PDBe:7p7s, PDBj:7p7s
PDBsum7p7s
PubMed35387982
UniProtA0A1B4XKT9

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