Structure of PDB 6i9r Chain 8 Binding Site BS01

Receptor Information
>6i9r Chain 8 (length=105) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIEDFITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQQERKMER
DTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIP
NYQPP
Ligand information
>6i9r Chain B (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agaguguagcuuaacacaaagcacccaacuuacacuuaggagauucaauu
gacgcucuga
<<<<<...<<<........>>>.<<.<<.......>>.>>....<<<<>>
>>.>>>>>..
Receptor-Ligand Complex Structure
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PDB6i9r Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S122 L123 R129 R133
Binding residue
(residue number reindexed from 1)		S39 L40 R46 R50
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0009653 anatomical structure morphogenesis
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6i9r, PDBe:6i9r, PDBj:6i9r
PDBsum6i9r
PubMed33910005
UniProtQ9NQ50|RM40_HUMAN Large ribosomal subunit protein mL40 (Gene Name=MRPL40)

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