Structure of PDB 6dzi Chain 8 Binding Site BS01

Receptor Information
>6dzi Chain 8 (length=228) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAVVTMKQLLDSGAHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYI
DKAYEFVKETVAHGGTVLFVGTKKQAQESIAEEATRVGMPYVNQRWLGGM
LTNFSTVHKRLQRLKELEAMEQTGGFEGRTKKEILMLTREKNKLERSLGG
IRDMQKVPSAVWVVDTNKEHIAVGEARKLGIPVIAILDTNCDPDVVDYPI
PGNDDAIRSAALLTKVIASAVAEGLQAR
Ligand information
>6dzi Chain h (length=1511) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaac
acaugcaagucgaacggaaaggcccuuucggggguacucgaguggcgaac
gggugaguaacacgugggugaucugcccugcacuuugggauaagccuggg
aaacugggucuaauaccgaauacacccugcuggucgcauggccugguagg
ggaaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggu
ggggugauggccuaccaaggcgacgacggguagccggccugagaggguga
ccggccacacugggacugagauacggcccagacuccuacgggaggcagca
guggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgug
agggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgc
aagugacgguaugugcagaagaaggaccggccaacuacgugccagcagcc
gcgguaauacguaggguccgagcguuguccggaauuacugggcguaaaga
gcucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugu
gggcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaa
uuccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggc
gaaggcgggucucugggcaguaacugacgcugaggagcgaaagcgugggg
agcgaacaggauuagauacccugguaguccacgccguaaacgguggguac
uagguguggguuuccuuccuugggauccgugccguagcuaacgcauuaag
uaccccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugac
gggggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcga
agaaccuuaccuggguuugacaugcacaggacgccggcagagaugucggu
ucccuuguggccugugugcagguggugcauggcugucgucagcucguguc
gugagauguuggguuaagucccgcaacgagcgcaacccuugucucauguu
gccagcacguuaugguggggacucgugagagacugccggggucaacucgg
aggaagguggggaugacgucaagucaucaugccccuuauguccagggcuu
cacacaugcuacaauggccgguacaaagggcugcgaugccgugaggugga
gcgaauccuuucaaagccggucucaguucggaucggggucugcaacucga
ccccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcggug
aauacguucccgggccuuguacacaccgcccgucacgucaugaaagucgg
uaacacccgaagccgguggccuaacccuuguggagggagccgucgaaggu
gggaucggcgauugggacgaagucguaacaagguagccguaccggaaggu
gcggcuggauc
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<
<<.<<<..<<<..<<.<..<<<<<.<....>.>>>.>>>..>>>>>....
..<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<..
....>>>>>......>>>>.....<<<<<<<<<<<....>>>>.>>>>>>
>....<......>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>
>>>.........<<<...<<<<<....>>>>.>>>>..>>.>>>>>>..<
<<<.......<<<....>>>......>>>>...<.<<<<<......<...
...>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))
>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....
<<<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>
>>>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....
<<<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<
....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<..
.<<...<<<<.........>>>>...>>>>>>>>..........<<<<<<
..<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>
>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.
.........<<<<<<<.......<<<<<<....<<<<<<....>>>>>>.
.<<.....>>.>>>>>>..<<<.<<<..<<<<<<.......<<<<<<<<<
....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<..<...
.<...<<<......>>>.>.....>..>>>.....<<<<<.....>>>>>
........>>>>.........>>>...>>>>>>>>>...>>>>>>>...>
>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..
>>....>>>......>>>>>>>......<....<<<<<<<........>>
>>>>>....>.....>>>>>>.....<<<<<<..........>>>>>>..
.....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<
<..<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>
>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>
>>>>>>.....
Receptor-Ligand Complex Structure
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PDB6dzi Zinc depletion induces ribosome hibernation in mycobacteria.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		R21 N24 K26 R95 G98 G99 T102 N103 R110 K132 K143 R146 I171 E175 K178
Binding residue
(residue number reindexed from 1)		R21 N24 K26 R95 G98 G99 T102 N103 R110 K132 K143 R146 I171 E175 K178
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dzi, PDBe:6dzi, PDBj:6dzi
PDBsum6dzi
PubMed30038002
UniProtA0QVB8|RS2_MYCS2 Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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