Structure of PDB 4v19 Chain 8 Binding Site BS01

Receptor Information
>4v19 Chain 8 (length=95) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTYFSSRKGKRKTVKAVIYRFLRLHSGLWLRRKAGYKKKLWKKTAARKRR
LREFVFCNKTQSKLLDKMTTSFWKRRNWYADDPYQKYQDRTNLKV
Ligand information
>4v19 Chain A (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacaacaaauacaaaaauacaccaaaauaaaauaaa
acauucaccuaacauuaaaguauaggagauagaaauuuuuauccugacgc
uauagagauaguaccguaagggaaagaugaaagaauaaaaguaaaaaaaa
gcaaagauuaccccuucuaccuuuugcauaaugguuuaaccagaaaaaau
cuaacaaagagaacuuuagcuagauaccccgaaaccagacgagcuaccca
ugagcaguuuaaaagaaccaacucaucuauguggcaaaauagugagaaga
cuuguagguagaggugaaaagccuaacgagccuggugauagcugguuguc
cgagaaagaauuuuaguucaaccuuaaaaauaccccaaaaacccuaaauu
ccaauguauuuuuaagagauagucuaaaaagguacagcuuuuuagaaacg
gauacaaccuugacuagagaguaaaucuuaauacuaccauaguaggccua
aaagcagccaucaauugagaaagcguuaaagcucaacaaauucaccaaca
uaaucccaaaaacuaauaacaaacuccuagcccaauaccggacuaaucua
uugaaacauagaagcaauaauguuaauaugaguaacaagaagccuuucuc
cucgcacacgcuuacaucaguaacuaauaauauacugauaauuaacaacc
aauaaaccaaaacaacacuaaaacguuuauuaauuacauuguuaacccaa
cacaggagugcaccaaggaaagauuaaaagaaguaaaaggaacucggcaa
acacaaaccccgccuguuuaccaaaaacaucaccucuagcauuacuagua
uuagaggcaaugccugcccagugacaaguuuaacggccgcgguacugacc
gugcaaagguagcauaaucacuuguucuccaaauaaggacuuguaugaau
ggccacacgaggguuuuacugucucuuacuuccaaucagugaaauuaacc
uucccgugaagaggcgggaauaaaaaaauaagacgagaagacccuaugga
gcuuuaauuaacuauuccaaaaguucuuaacauggacuagcaauuucggu
uggggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagac
aaaccagucaaaauaaucacuuauugauccaaaauuuugaucaacggaac
aaguuacccuagggauaacagcgcaauccuguucuagaguuccuaucgac
aauaggguuuacgaccucgauguuggaucaggacacccaaauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggagcaauccaggucgguuucuaucuauuauaaauuucuccc
aguacgaaaggacaagagaaaugggaccaaccucacaaacgcgucucaga
gauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaauccagcc
cuagaacagggcaca
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<<<<..<<<......>>>...<<<..<<<<........>>>>.>>>....
>>>>>.>>>...<<<.....>>>......>.>>>>......>.>>..<<<
<<.....<<<<....>>>>...<<<<<<<<<<<.....<<........>>
.....>>>>>>>>>>>......<<<<<<<<<......>>>>>>>>>...<
<......>>....<<<<.<<<..................<....<<<...
......>>>....>.......<<<......>>>.................
.......................>>>>>>>........>>>>>...<<<<
<......>>>>>.........>>>>>.<......<<..<<<<..>>>><<
<..<<<<........<<<<<....<<....>>..>>>>>......<<<..
<<<<<<<.................>>>>>>>.......>>>.....<<..
....>>.>>>>.....>>>..<<<<....<<<<<<<.<<...........
....<<<<<<<<..<<<.........>>>...<<<<<<............
.>>>>>>...<<<<.<<<..<<<<<..>>>..>>>>><<<<<<....>>>
>>>........<...........<<<<<.......>>>>>.....>....
>>>.>..>>.>>>>>>......>>.>>>>>>>.>>>>.>>.....>....
.<<<<<........>>>>>.......<<<.<<<.<<......<<<<.<<<
<<<..<<<<..<<<.<<<<.<<<..>>>....>>>>.>>>.>>>>..<<<
<.....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<
......>>>...>>.>>>>..........<<<<..>>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<.<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>..>
....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<<<<<..
...............>>>>>>><<<<<...............>>>>>.<<
<.<.<<<<.................>>>>..>>>>.>>.........<<<
<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v19 The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T95 S98 S99 R100 K101 K103 R104 K105 T106 K108 R113 H118 R124 K126 A127 G128 K131 K132 L133 W134 K135 R140 R142 R143 K152 T153 Q154 K156 K160 F165 W166 R168 R169 D182 V188
Binding residue
(residue number reindexed from 1)		T2 S5 S6 R7 K8 K10 R11 K12 T13 K15 R20 H25 R31 K33 A34 G35 K38 K39 L40 W41 K42 R47 R49 R50 K59 T60 Q61 K63 K67 F72 W73 R75 R76 D89 V95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v19, PDBe:4v19, PDBj:4v19
PDBsum4v19
PubMed25271403
UniProtF1SVC5

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