Structure of PDB 6gsl Chain 7E Binding Site BS01

Receptor Information
>6gsl Chain 7E (length=138) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYER
VDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEI
PRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
Ligand information
>6gsl Chain 13 (length=1512) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuguuggagaguuugauccuggcucagggugaacgcuggcggcgugccua
agacaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcg
gacgggugaguaacgcgugggugaccuacccggaagagggggacaacccg
gggaaacucgggcuaaucccccauguggacccgccccuuggggugugucc
aaagggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugg
ugggguaauggcccaccaaggcgacgacggguagccggucugagaggaug
gccggccacaggggcacugagacacgggccccacuccuacgggaggcagc
aguuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuu
ggaggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccc
ccgacgaggggacugacgguaccgggguaauagcgccggccaacuccgug
ccagcagccgcgguaauacggagggcgcgagcguuacccggauucacugg
gcguaaagggcguguaggcggccuggggcgucccaugugaaagaccacgg
cucaaccgugggggagcgugggauacgcucaggcuagacggugggagagg
gugguggaauucccggaguagcggugaaaugcgcagauaccgggaggaac
gccgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaa
agcguggggagcaaaccggauuagauacccggguaguccacgcccuaaac
gaugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaa
gcgcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauuga
cgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugg
ggugccccgcgaggggagcccuagcacaggugcugcauggccgucgucag
cucgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgc
cguuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaa
agcgggaggaaggaggggacgacgucuggucagcauggcccuuacggccu
gggcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaa
cggggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaa
cccgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccg
cggugaauacguucccgggccuuguacacaccgcccgucacgccauggga
gcgggcucuacccgaagucgccgggagccuacgggcaggcgccgagggua
gggcccgugacuggggcgaagucguaacaagguagcuguaccggaaggug
cggcuggacacc
........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<.
.<<<.<<<..<<<..<<.<<<<<<<<<<<...>>>>>>>>>>>.>>>>>.
.....<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<
<......>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>
>..<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<
<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>.
..>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>
>>>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..
<<<<......<<<<....>>>>.....>>>>....<<<<<.........<
<<.....>>>...........>>>>>......<<<<<(((...<<<<<..
...<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<
<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<
.....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<
<<<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>....
.......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>...
.<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.......
...<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>
>....<<......>>...>>>>>>>>.<<<.<<<..<<<<<<.......<
<<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<
<<<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<...
.>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>
>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....
>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<.....
...>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>
>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..
<<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>
>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gsl Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Resolution3.16 Å
Binding residue
(original residue number in PDB)
M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 K21 S29 R30 F31 K32 K56 K88 P89 G90 R92 Y94 G96 V97 R102 R105 S113 T114 S115 K116 G128 V129 G130 E132
Binding residue
(residue number reindexed from 1)
M1 L2 T3 P5 D8 T11 R12 R14 N15 R18 K21 S29 R30 F31 K32 K56 K88 P89 G90 R92 Y94 G96 V97 R102 R105 S113 T114 S115 K116 G128 V129 G130 E132
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gsl, PDBe:6gsl, PDBj:6gsl
PDBsum6gsl
PubMed29931292
UniProtP0DOY9|RS8_THET8 Small ribosomal subunit protein uS8 (Gene Name=rpsH)

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