Structure of PDB 5el4 Chain 71 Binding Site BS01

Receptor Information
>5el4 Chain 71 (length=133) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPR
RSDQNVRGTVSLPHGLGFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRA
LEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS
Ligand information
>5el4 Chain 3K (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggucguuagcucaguugguagagcaguugacuuuuaaucaauuggucgc
agguucgaauccugcacgacccacca
<<<<.<<..<.<..........>.>.<<<<<.......>>>>>.......
<<<.......>>>..>>.>>>>....
Receptor-Ligand Complex Structure
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PDB5el4 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution3.15 Å
Binding residue
(original residue number in PDB)
R52 R53 K167
Binding residue
(residue number reindexed from 1)
R50 R51 K72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5el4, PDBe:5el4, PDBj:5el4
PDBsum5el4
PubMed26791911
UniProtQ5SLP7|RL1_THET8 Large ribosomal subunit protein uL1 (Gene Name=rplA)

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