Structure of PDB 5e81 Chain 71 Binding Site BS01

Receptor Information
>5e81 Chain 71 (length=133) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPR
RSDQNVRGTVSLPHGLGFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRA
LEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS
Ligand information
>5e81 Chain 3K (length=70) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggucguuagcucagugagcaguugacuuuuaaucaauuggcgcagguuc
gaauccugcacgacccacca
<<<<.<<...<<<...>>>..<<<<<.......>>>>>.....<<<<...
....>>>>.>>.>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5e81 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		R52 R53
Binding residue
(residue number reindexed from 1)		R50 R51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5e81, PDBe:5e81, PDBj:5e81
PDBsum5e81
PubMed26791911
UniProtQ5SLP7|RL1_THET8 Large ribosomal subunit protein uL1 (Gene Name=rplA)

[Back to BioLiP]