Structure of PDB 8uu8 Chain 7 Binding Site BS01

Receptor Information
>8uu8 Chain 7 (length=64) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKMKTHRGSAKRFKRTGSGKLKRRHGFTSHMFANKSQKQKRKLRKSAMVS
AGDFKRIRQMVAKM
Ligand information
>8uu8 Chain A (length=2901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuaggguaccgaauucagauaaacuccga
augccauguacuuauacucgggagucagacugcgagugauaagauccgua
gucgaaagggaaacagcccagaccaccaguuaagguccccaaauauaugu
uaaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuag
aagcagccaccauugaaagagugcguaauagcucacuggucgagugaccc
cgcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaa
ccuagguucgugguaggagagcguucuaagggcggugaagucagaccgga
aggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaag
aagggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcu
cguccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggc
gauggacaacagguagagauuccuguaccagugcuaauuguuuaaccgau
ggggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaa
gcagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcug
ugauggggaaguacggaaguuccugauuucacgcugucaagaaaagccuc
uaggaagaguaguacugcccguaccgcaaaccgacacagguagaugagga
gagaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaau
gaccccguaacuucgggagaaggggugcucuauuagggugcaagcccgag
agagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucu
cugcaaaaccguaaggugacguauaggggcugacgccugcccggugcugg
aagguuaagaggagugcuuagcuucggcgaagguacgaauugaagcccca
guaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugu
cggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucuc
aacgagagacucggugaaauuauaguaccugugaagaugcagguuacccg
cgacaggacggaaagaccccguggagcuuuacugcaaccugauauggaau
guuuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcu
agcauacgaggaggcaauggugggauacuacccuggcuguaugaccauuc
uaacccgccacgcuaagcgcguggggagacagugucaggugggcaguuug
acuggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccu
cagaauggauggaaaucauucgcagaguguaaaggcacaagggagcuuga
cugcgagacugacaagucgagcagggacgaaagucgggcuuagugauccg
gugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccggg
gauaacaggcuuaucucccccaagaguccacaucgacggggagguuuggc
accucgaugucggcucgucgcauccuggggcuguagucggucccaagggu
ugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgu
gagacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagc
uguccuuaguacgagaggaccgggauggacacaccgcugguguaccaguu
guuccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcu
gaaagcaucuaagcgugaagccccccucaagaugagauuucccauuucuu
cggaaaguaagaucccugaaagaugaucagguagauagguuuggagugga
aguguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaac
c
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>..
...>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>
>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<
...........<<..<<<<<<<<<<<......<<<<<.<<<..<<<<...
....>>>>..>>>.........<<......>>...>>>>>..>>>>>>>>
>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<
<<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<...
.>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<
<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>
...>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...
<<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..
<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>
>...>>.............>>>>>...>>>...>>>>........>>>>>
..>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<
.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<....
.<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>...
>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<
<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<
..<<<<..<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<.......>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.
>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<
<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<
<.<<<<<<.<<<...........<<<<<..<<<.......<<<<<<<...
.>>>>>>>....>>>............>>>>>..>>>.>>>>>>.>>>>>
....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<
<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...
<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<
<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>
.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>
.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.
<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<
<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<
<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<
...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<..
..>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<...
.<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8uu8 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P2 K3 M4 K5 T6 H7 R8 K12 K15 T17 S19 K23 R24 G27 F28 S30 H31 F33 N35 Q38 K39 Q40 K43 R45 M49 D54 R57 Q60
Binding residue
(residue number reindexed from 1)
P1 K2 M3 K4 T5 H6 R7 K11 K14 T16 S18 K22 R23 G26 F27 S29 H30 F32 N34 Q37 K38 Q39 K42 R44 M48 D53 R56 Q59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uu8, PDBe:8uu8, PDBj:8uu8
PDBsum8uu8
PubMed38407413
UniProtA0A660JIB9

[Back to BioLiP]