Structure of PDB 8uu4 Chain 7 Binding Site BS01

Receptor Information
>8uu4 Chain 7 (length=64) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKMKTHRGSAKRFKRTGSGKLKRRHGFTSHMFANKSQKQKRKLRKSAMVS
AGDFKRIRQMVAKM
Ligand information
>8uu4 Chain A (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaaga
aggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguuga
uccagagauuuccgaaugggggaacccacuaucuuuagucggauaguauc
cuuacgugaauacauagcgugaggaaggcagacccagggaacugaaacau
cuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggcg
agcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguuguag
gacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugga
aaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccuc
cagaguggauccugaguacgacggaacacgugaaauuccgucggaauccg
ggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaacc
aguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacagu
uccugaaaccgugugccuacaaguaguuagagcccguuaaugggugauag
cgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguuaa
gcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaag
uaacaggucguagacccgaaaccaggugaucuacccauguccaggaugaa
gguaagguaauacuuacuggagguccgaacccacgcacguugaaaagugc
ggggaugagguguggguagcggagaaauuccaaucgaacuuggagauagc
ugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucaug
gagguagagcacuguuuggacuaggggcccgguuaccgaauucagauaaa
cuccgaaugccauguacuuauacucgggagucagacugcgagugauaaga
uccguagucgaaagggaaacagcccagaccaccaguuaagguccccaaau
auauguuaaguggaaaaggaugugggguugcuuagacaaccaggauguug
gcuuagaagcagccaccauugaaagagugcguaauagcucacuggucgag
ugaccccgcgccgaaaauguaccggggcuaaacauauuaccgaaacugug
gaugaaccgguucgugguaggagagcguucuaagggcggugaagucagac
cggaaggacugguggagcgcuuagaagugagaaugccgguaugaguagcg
aaagaagggugagaaucccuuccaccgaauaucuaagguuuccugaggaa
ggcucguccgcucaggguuagucgggaccuaagccgaggccgauaggcgu
aggcgauggacaacagguagagauuccuguaccagugcuaauuguuuaac
cgauggggugacacagaaggauagggaaucgcacgaauggaaaugugcgu
ccaagcagugagugugagaaguaggcaaauccgcuucuugcgaagcauga
gcugugauggggaagcggaaguuccugauuucacgcugucaagaaaagcc
ucuaggaagaguaguacugcccguaccgcaaaccgacacagguagaugag
gagagaauccuaaggugagcgagagaacucucguuaaggaacucggcaaa
augaccccguaacuucgggagaaggggugcucuauuagggugcaagcccg
agagagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggu
cucugcaaaaccguaaggugacguauaggggcugacgccugcccggugcu
ggaagguuaagaggagugcuuagcuucggcgaagguacgaauugaagccc
caguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuu
gucggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacuguc
ucaacgagagacucggugaaauuauaguaccugugaagaugcagguuacc
cgcgacaggacggaaagaccccguggagcuuuacugcaaccugauaugga
auguuuguaccgcuuguacaggauagguaggagccgaagagacgugugcg
cuagcauacgaggaggcaauggugggauacuacccuggcuguaugaccau
ucuaacccgccacgcuaagcgcguggggagacagugucaggugggcaguu
ugacuggggcggucgccuccuaaagaguaacggaggcgcccaaagguucc
cucagaauggauggaaaucauucgcagaguguaaaggcacaagggagcuu
gacugcgagacugacaagucgagcagggacgaaagucgggcuuagugauc
cggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccg
gggauaacaggcuuaucucccccaagaguccacaucgacggggagguuug
gcaccucgaugucggcucgucgcauccuggggcuguagucggucccaagg
guugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacguc
gugagacaguucggucccuauccgucgcgggcgcaggaaauuugagagga
gcuguccuuaguacgagaggaccgggauggacacaccgcugguguaccag
uuguuccgccaggagcaucgcuggguagcuauguguggcagggauaaacg
cugaaagcaucuaagcgugaagccccccucaagaugagauuucccauuuc
uucggaaaguaagaucccugaaagaugaucagguagauagguuuggagug
gaaguguagcgauacauggagcggacaaauacuaaucgaucgaggacuua
acc
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<....
..>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>>
>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<
<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...........
....<<....>>....]].........<<<<....>>>>...........
..}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.......>>...>>>...<<....>>..<<<<.....>>>>......>
>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....
<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>
>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>
.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<<
<.....<<<...<<<<<<<<...<<.<<<.>>>..>>...>>>>>>>>..
>>.>.....>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>
>.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....
<<<<<<...........<<..<<<<<<<<<<.......<<<<<.<<...<
<<<.......>>>>...>>.........<<......>>...>>>>>...>
>>>>>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>
><<<<<<..>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<
<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<.
...<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...
<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>..
.>>>...>>...<<<<<........>>>>>))<<<<<<<<.<<......<
<...<<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.
<<..<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..
>>>>>...>>...........>>>>>...>>>...>>>>........>>>
>>..>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<..
...<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>.
..>>>>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<
<<..<<<<..<<...<<<<<<.<<<..>>>..>>>>>>...>>..>>>>>
>>>>..>>>>><<<<<<.......>>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>
>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<
<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<
<<<..<<<<<.<<<...........<<<<<..<<<.......<<<<<<<.
...>>>>>>>....>>>............>>>>>..>>>.>>>>>..>>>
>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>.
.<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<
<...<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>.
..<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......
<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>
>>.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>
>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>
>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<
....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<.
.<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<
<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<
<<...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<
<..>>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<.
...<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>
>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uu4 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		P2 K3 M4 K5 T6 H7 R8 K12 R13 K15 T17 S19 R24 G27 F28 S30 H31 F33 N35 K39 Q40 K41 K43 R45 K46 D54 K56 R57
Binding residue
(residue number reindexed from 1)		P1 K2 M3 K4 T5 H6 R7 K11 R12 K14 T16 S18 R23 G26 F27 S29 H30 F32 N34 K38 Q39 K40 K42 R44 K45 D53 K55 R56
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uu4, PDBe:8uu4, PDBj:8uu4
PDBsum8uu4
PubMed38407413
UniProtA0A660JIB9

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