Structure of PDB 8qbn Chain 7 Binding Site BS01

Receptor Information
>8qbn Chain 7 (length=387) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLSQSDEDVIRLIGQHLNGLGLNQTVDLLMQESGCRLPSVMLPPRRLQTL
LRQAVELQRDRCLYHNTKLDSVSLLIDHVCSRRQFPCYTQQILTEHCNEV
WFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIA
WSPDDNYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDG
KRFVTGGQRGQFYQCDLDGNLLDSWEGVRVQCLWCLSDGKTVLASDTHQR
IRGYNFEDLTDRNIVQEDHPIMSFTISKNGRLALLNVATQGVHLWDLQDR
VLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAE
LTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWGPAP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8qbn Chain 7 Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qbn Non-canonical substrate targeting by the supramolecular CTLH E3 ligase reveals an WDR26-YPEL5 regulatory module
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C300 H303 H320 C322
Binding residue
(residue number reindexed from 1)		C62 H65 H78 C80
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0034657 GID complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qbn, PDBe:8qbn, PDBj:8qbn
PDBsum8qbn
PubMed38759627
UniProtQ9H7D7|WDR26_HUMAN WD repeat-containing protein 26 (Gene Name=WDR26)

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