Structure of PDB 7r7c Chain 7 Binding Site BS01

Receptor Information
>7r7c Chain 7 (length=104) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQARNQLANKPSKTKVKKEQSLARLYGAKDLNIPTLNRAIVPGVKIRRGK
KGKKFIADNDTLTLNRLITTIGDKYDDIAESKLEKARRLEEIRELKRKEI
ERKE
Ligand information
>7r7c Chain 1 (length=226) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcggucgaucguuucccucaggauauuuuugguaagcagaacuacccugu
ugagcuugacucuaguuugacauugugaagagacauagaggguguagaau
aagugggagcuucggcgccagugaaauaccacuaccuuuauaguuucuuu
acuauugucagguggggaguaaaguuaccacagggauaauuguggcaguc
uugcugaccgucgugagacagguuag
<<<<....>>>>.<<<....>>>...<<<<<.....>>>>>...<<<<<<
.<<<<<<..<<<<.<.<<<<<....<<<<<<<<<..<<<.<.........
.<<<<<..<<<..>>>............>>>>>..>>>>...>>>>>>>>
>.....>>>>>.>..>>>>..>>>>>.>.>>>>>>........<<<<<..
>>>>><<<<<<<....>>>.>>>>..
Receptor-Ligand Complex Structure
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PDB7r7c Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.71 Å
Binding residue
(original residue number in PDB)		K51 Q54 R58 Y60 G93 K94 K95 F99
Binding residue
(residue number reindexed from 1)		K17 Q20 R24 Y26 G49 K50 K51 F55
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0008298 intracellular mRNA localization
GO:0017148 negative regulation of translation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor
GO:0101031 protein folding chaperone complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r7c, PDBe:7r7c, PDBj:7r7c
PDBsum7r7c
PubMed36482249
UniProtP43586|LOC1_YEAST 60S ribosomal subunit assembly/export protein LOC1 (Gene Name=LOC1)

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