Structure of PDB 6ywx Chain 7 Binding Site BS01

Receptor Information

>6ywx Chain 7 (length=84) Species: 367110 (Neurospora crassa OR74A)

AKPYLVGRAWTQRLPVYHLAKRGGNKKLTQIKKVQGDGQALRRDLAQFLG
LEVKEVRVKVPTGHLEVDGHRREEIVKFLDGLGF

Ligand information

>6ywx Chain A (length=2838)

guaauggauauaaagcuuauguuuauauauauauauaaguauauaaagag
acuacuaccaauagcuacacuauguauuaaggagaguauaacuuaauuua
uguuuaugauagagguuaucaacauaugaacucuuagagaaauuacuuaa
uaaacgaagugaauugaaauaucuuauuaacuucaggaaaagaaaucaaa
cgagauucuaugauuagugugaacgaaaauagagcagccuauuaaaauaa
guaaaauggcuuuaaagcuguuugaauauuguggggaaccuuccucaaag
gcuaaauauaauacaugaguuacagagaaaaguaccgugagggaaagcuu
ugaaauaguaguuuuauaagcagcucaagcaauaagaaagcgagagcgua
ccuuuugcauaaugggucaccaaguuaauuuuagaugcgagcgaauuaga
ugugcauaguuaaaccgaucauuaaaauaaugaauagugucuaaaguuag
acccgaagccuggugaucuuacuauagucaggacuauaaagguccgaacg
gguuaucguugcaaagauauccgaagaacuaugguaagcgagugaaagac
aacacugacuaggauagcugguuuucugcgaaaccuauaauaguaggcaa
uuuaaguaacaucuuaguagguacagaacuuaaucucagacaagauguag
auuuucauaccuagguaugaaaugcauuuuuuuuuguauacaucggggga
ucgugaagauuuuaucggugaguauguagacucggaaugacaaagaugaa
ucuugaauaaucagacauagaaugauaagguuguaugucaaaagggaaac
agcccagaacaagaguuaagguuccaaaauuauuauuaagugaaauaaag
aaaguuuuuauauaagucgacaagaagaugggcuuggaagcagccauaau
uuaaagaucucguaacagagcacuuguuaaaucuuaaaagcaucgaaaau
uuaacggaucuaaauaauauaccgaaaccuuguccauauguaacauuagu
aauaauauuaauguuauuugaugggguagcagaacguugagugaaucuua
gauuuuuuuuuuauaacuaaauauagaugauaacucaagugagaauggug
acaugaguaacaaaaaagaguuuaagguaccuaaaagguaucuuagaguc
ucgccuaaagcuuauggcuacgucaaguaacggccucuaaguuuauaauc
ugaagauuaugacgaugagaaaacuuugguaccaacauuuaaaagugaaa
auugugcaggaaggauaaaccguaccuagaaucugaaacaaguaagcuag
uagagaauacgaaggcgugaaugagauaacaaucauaaaggaacucggca
aacuaacuaccguaacuuagggauaaggagagcucauuagucucgaacga
guaaaaaggaagaagcauggaauauuguuguacgacuguuuaauuaaaac
aaagcacuuugcaaaaagacgauaagucuaaguauugagugugauuucug
cccgaugccggcugguuaacgaauuuucuaaauugaaaaaaaauuugguu
ucagaggaacccccgguuaauggcggccuuagcgugaggguccuaaggua
gcgaaaugccuuggccguuaaaugcggucuugcaugaaugauguaacgau
acaacagcugucucuaugauugacucagugaaauuggaauaacugugcag
auacaguuuaccucuaguuagacgagaagacccuaugcagcuuuacuguu
acuaauuauugaauacgauucugaaaauuuccaguguaaaagguaaucga
uaagauauaauugaaacaccuuuauuuuucuaucguauuauuaaaccuua
aauuaaggaacaauuguuagaagacaguuuaugcggggcacaggccccau
aaagaguaaaugggugugucuaaaauguuugcaauuuuuuauaguauaua
ucaaaucaucuuuaugcuauucauagaccuuggguacaguauaaaaauua
uauauguauuaauuuacauauauuuuuucuaagaaauuagguaagauuuu
guuuauagagaaauuagauguaaaaaaaaaaucuuaugagggcggauccg
cuucuaauauuuuuuuguaguuauuauuauaauaauaaucauguuuauua
cuuaaaaagcuuaauggcuuaaucuugccuuacuguuugauuaacaacaa
aucuuacagucgcguaagcggggcauaggaucacaagauacaaaaaggaa
agaucuuggauuuuuggaaaagcuacgcuagggauaacaggcuaauuugc
gcaagaguguacaaaaugagugcgcgguuuggcaccuccggcuugacuaa
uccucauggaugcagaaacuauguaggguacgacuguucgucgauuaaaa
aguuacaugagcuggguuaaauacgucgugagacaguaugguuucuaucu
ucuagagggaauuagaauauaauaaggauuaaccuuuguacgaaaggaac
augggguacuauuguuaacaguuuuauuaaccucugguuuaccuguuguu
uaugugccuuagggauguuaccgucacuugaguaaauacaauagcauaag
cauggcaggaaagcuaaguuagucaaaaauaagugcugaaagcauauagg
cacgaaauuuaccuuaagauauuucuuaaauauacguaagaaaauauuac
guuaauaggcuuaguuuguaauaaucuagagauuuuaaggaacuaaguac
uaauuuuauaaaaaacugaaugauuaauauaucuuaca

<<<<..<<<<<<.......<<<<<<<<<..>>>>...<<<.......<<<
<<<<<<<......<<.....<<<<<<<<..<<<<<<.....>>.....<<
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....<<<<<<.....<<....>>......>>>>>.>.........<<...
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...<<<<<<<<....>>>>>>>>........<<<<<..[[[[>>>>>...
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.....>>>>>>>>>>.......<<<<..<<.........>>..>>>>...
<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<.......
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..........>>>>.>>..<<.....<.......<<<..<<<<...>>>>
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<<<<<<<<......>>>>>>>>>................<<<<<<<....
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>>.>>>>.>>>.>>>>...<<<<<<<<<..>>>>>>>>>........>>>
>......<<<...(((>>>...>>>>>>>...<<<<..<<<.........
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.>>>>>>>............>>>>..>>>>>>.......<<<<.<...<<
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.>>>>>>>.....<<<<<<...<<<<<...<<<<<...............
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>>>...>>>>.>>>>>...>>>.>>>....<<<.<<<<<.......>>>>
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>>.....>>>....>>>>>>>>.....>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ywx Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): A90 W91 T92 R94 Y98 K102 R103 G104 N106 K113 K114 V141 T143
• Binding residue (residue number reindexed from 1): A9 W10 T11 R13 Y17 K21 R22 G23 N25 K32 K33 V60 T62

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005762 mitochondrial large ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ywx, PDBe:6ywx, PDBj:6ywx
• PDBsum: 6ywx
• PubMed: 33056988
• UniProt: Q7S518|IMG2_NEUCR Large ribosomal subunit protein mL49 (Gene Name=img2)