Structure of PDB 6ywv Chain 7 Binding Site BS01

Receptor Information

>6ywv Chain 7 (length=84) Species: 367110 (Neurospora crassa OR74A)

AKPYLVGRAWTQRLPVYHLAKRGGNKKLTQIKKVQGDGQALRRDLAQFLG
LEVKEVRVKVPTGHLEVDGHRREEIVKFLDGLGF

Ligand information

>6ywv Chain A (length=2529)

guaauggauauaaagcuuauguuuauauauauauauaaguauauaaagag
acuacuaccaauagcuacacuauguauuaaggagaguauaacuuaauuua
uguuuaugauagagguuaucaacauaugaacucuuagagaaauuacuuaa
uaaacgaagugaauugaaauaucuuauuaacuucaggaaaagaaaucaaa
cgagauucuaugauuagugugaacgaaaauagagcagccuauuaaaauaa
guaaaauggcuuuaaagcuguuugaauauuguggggaaccuuccucaaag
gcuaaauauaauacaugaguuacagagaaaaguaccgugagggaaagcuu
ugaaauaguaguuuuauaagcagcucaagcaauaagaaagcgagagcgua
ccuuuugcauaaugggucaccaaguuaauuuuagaugcgagcgaauuaga
ugugcauaguuaaaccgaucauuaaaauaaugaauagugucuaaaguuag
acccgaagccuggugaucuuacuauagucaggacuauaaagguccgaacg
gguuaucguugcaaagauauccgaagaacuaugguaagcgagugaaagac
aacacugacuaggauagcugguuuucugcgaaaccuauaauaguaggcaa
uuuaaguaacaucuuaguagguacagaacuuaaucucagacaagauguag
auuuucauaccuagguaugaaaugcauuuuuuuuuguauacaucgggguu
aucggugaguauguagacucggaaugacaaagaugaaucuugaauaauca
gacauagaaugauaagguuguaugucaaaagggaaacagcccagaacaag
aguuaagguuccaaaauuauuauuaagugaaauaaagaaaguuuuuauau
aagucgacaagaagaugggcuuggaagcagccauaauuuaaagaucucgu
aacagagcacuuguuaaaucuuaaaagcaucgaaaauuuaacggaucuaa
auaauauaccgaaaccuuguccauauguaacauuaguaauaauauuaaug
uuauuugaugggguagcagaacguugagugaaucuuagauuuuuuuuuua
uaacuaaauauagaugauaacucaagugagaauggugacaugaguaacaa
aaaagaguuuaagguaccuaaaagguaucuuagagucucgccuaaagcuu
auggcuacgucaaguaacggccucuaaguuuauaaucugaagauuaugac
gaugagaaaacuuugguaccaacauuuaaaagugaaaauugugcaggaag
gauaaaccguaccuagaaucugaaacaaguaagcuaguagagaauacgaa
ggcgugaaugagauaacaaucauaaaggaacucggcaaacuauaccguaa
cuuagggauaaggagagcauggaauauuguuguacgacuguuuaauuaaa
acaaagcacuuugcaaaaagacgauaagucuaaguauugagugugauuuc
auguaacgauacaacagcugucucuaugauugacucagugaaauuggaau
aacugugcagauacaguuuaccucuaguuagacgagaagacccuaugcag
cuuuacuguuacuaauuauugaauacgaaucguauuauuaaaccuuaaau
uaaggaacaauuguuagaagacaguuuaggccccauaaagaguaaauggg
ugugucuaaaauguuugcaauuuuuuauaguauauaucaaaucaucuuua
ugcuauucauggguacaguauaaaaauuuaagaaauuagguaagauuuug
uuuauagagaaauuagauguaaaaaaaaaaucuuaugagggcggauccgc
uucuaauauuuuuuuguaguuauuauuauaauaauaaucauguuuauuac
uuaaaaagcuuaauggcuuaaucuugccuuacuguuugauuaacaacaaa
ucuuacagucgcguaagcggggcauaggaucacaagauacaaaaaggaaa
gaucuuggauuuuuggaaaagcuacgcuagggauaacaggcuaauuugcg
caagaguguacaaaaugagugcgcgguuuggcaccucgaugucggcuuga
cuaauccucauggaugcagaaacuauguaggguacgacuguucgucgauu
aaaaaguuacaugagcuggguuaaauacgucgugagacaguaugguuucu
aucuucuagagggaauuagaauauaauaaggauuaaccuuuguacgaaag
gaacaugggguacuauuguuauauaacaguuuuauuaaccucugguuuac
cuguuguuuaugugccuuagggauguuaccgucacuugaguaaauacaau
agcauaagcauggcaggaaagcuaaguuagucaaaaauaagugcugaaag
cauauaggcacgaaauuuaccuuaagauauuucuuaaauauacguaagaa
aauauuacguuaauaggcuuaguuuguaaggaacuaaguacuaauuuuau
aaaaaacugaaugauuaauauaucuuaca

<<<<..<<<<<<.......<<<<<<<<<..>>>>...<<<.......<<<
<<<<<<<......<<.....<<<<<<<<<.<<<<<<.....>>.....<<
<<<<................>>>>>>....>>>>..<<....>>......
....<<<<<<.....<......>......>>>>>.>.........<<...
.>>..<<<<<<.....<<....>>....>>>>>>..<<............
...<<<<<<<<....>>>>>>>>........<<<<<..[[[[>>>>>...
>>......>>>>>>>>>.................<<....>>....>>..
.....>>>>>>>>>>.......<<<<..<<.........>>..>>>>...
<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<.......
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.<<.<..<<<<<<<....<<<<<<<<<<..<<<<<....>>.>>>...<<
<..<<<<........>>>>.>>>....>>>>>>>>>>....<<.....>>
.......>>>>>>.>..>.>>..<<<<<<....<<<<<....>>>>>..<
<<<<<<...<<<<<<.<<.....<<<......<<<<<<.<<<<<<<.<.<
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<<<<<<.<<<......>>>.>>>>>>....<<<......>>>...<<<<<
.<<...<<<(((.....<<<<<<.....<<......<<..<<<<<<<...
.....<<<<<<.<....<<<<.......>>>>....>........<<<..
....>>>..>>>>>>......>>>>>>>.>>...........)))>>...
>>>>>>.>>>...>>>>>>><<<<..<<<<<<<<<<<<....>>>>>>>>
>>>>...>>>>....>>>>>>..<<<<<<..<<<....<<..<<..<<..
.>>..>>..>>....>>>.>>>>>>........>>>>>><......<<..
...<<<.<<<<<<<<<<<.....>>>>>>>>>>>.>>><<<<<...<<<<
<.<<........((...<<<.<<<...<<<.<<<<<<<..>>>>>>>>>>
...>>>....)).........<<<.<<..(((((..>>.>>>........
......>>>..>>......<<......>>>>>>>..<<<.....>>>..>
>>>>....<<<<....<<<<<<<<.<<.................<<....
<<..>>.....>>..............<<<<<<<<<..<<<.........
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>.....>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....
<<<<<........>>>>>..<<<<<<<..<<<.<<...<<<<<<<.<<<<
<<..<<<<<..<<<<<.<<..<<<<<<<.>>>>>>>......<<<<....
.>>>>....>>.>>>>>...>>>>>....<<<<<<...........>>>>
.>>..<<.....<.......<<<..<<<<...>>>>..>>>.>.......
...<<<<<..>>>>>.......................<<<<<<<.....
<<<<.........>>>>.<<<<..<<<<<<<.<<<.<<.<<<<<..>>>>
>>>>>>.>>>.>>>>...<<<<<<<<<..>>>>>>>>>........>>>>
......<<<...(((>>>...>>>>>>>...<<<<..<<<.........>
>>..>>>>.<<<....>>>.>>))).......<<<<<<.<...]]]]...
>>>>>>>............>>>>..>>>>>>>......<<<<.....<<<
<<...<.........>...>>>>>.....>>>.>.>>......<<<..<<
<<...<<<<<<<<.........>>>>>..>>>..<<<<.....>>>>...
....>>>>......>>>.......<<<<<<<....>>>.>>>>....>>.
.>>>.>>>>>>>.....<<<<<<...<<<<<...<<<<............
......>>......<<<<<<<<>>>>>>>>>>.<<<<<<...<<<<...<
<<<<<<<<<<<<<.<<<..>>>...<<<<...)))))..>>>>.......
.>>>>>>>>>..>>>>>...>>>>.>>>>>>..<<<.<..<<<<<.....
......>>>>>...>>>>.>>>>>...>>>.>>>....<<<.<<<<<...
....>>>>>....<<<<<<<<<<<<....>>.>>>>>>>.>>>.....>>
>....>>>>>>>>.....>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ywv Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
• Resolution: 3.03 Å
• Binding residue (original residue number in PDB): A90 W91 T92 R94 Y98 K102 R103 N106 K107 K113 K114 V141 T143
• Binding residue (residue number reindexed from 1): A9 W10 T11 R13 Y17 K21 R22 N25 K26 K32 K33 V60 T62

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005762 mitochondrial large ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ywv, PDBe:6ywv, PDBj:6ywv
• PDBsum: 6ywv
• PubMed: 33056988
• UniProt: Q7S518|IMG2_NEUCR Large ribosomal subunit protein mL49 (Gene Name=img2)