Structure of PDB 6ray Chain 7 Binding Site BS01

Receptor Information
>6ray Chain 7 (length=587) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRDYAQDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDL
DDLAEFNESLAEAVVDNCRRYTSIFSDVIAELLPSALDVYIEHRLMMEQR
DERNSFPSELMKRFEVGFKPIREVKAQHIGKLVTVRVTRCTEVKPMMVVA
TETYQPVNSLSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKQE
HSDQVPVGHIPRSTIMCRGEVTRMAQPGDHIVVSFLPLMGLLFLQAHRII
CINKNDEISDKDPEELEELAQDDFYERLATSLAPEIYGHLDVKKALLLLL
VGGVDKRPDGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRG
SSGVGLTAAVMDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIH
EVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPA
ALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNLM
RRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTSARNLLGI
LRLSTALARLRLSDSVEKDDVAEALRLLEMSKDSLNQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6ray Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Resolution4.28 Å
Binding residue
(original residue number in PDB)		V418 M419 K471
Binding residue
(residue number reindexed from 1)		V360 M361 K412
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0000727 double-strand break repair via break-induced replication
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006279 premeiotic DNA replication
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0042555 MCM complex
GO:0071162 CMG complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ray, PDBe:6ray, PDBj:6ray
PDBsum6ray
PubMed31484077
UniProtQ9XYU0|MCM7_DROME DNA replication licensing factor Mcm7 (Gene Name=Mcm7)

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