Structure of PDB 5el5 Chain 6E Binding Site BS01

Receptor Information
>5el5 Chain 6E (length=151) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVNYQVPMEVSPRRQQSLALRWL
VQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHY
R
Ligand information
>5el5 Chain 13 (length=1493) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccguggucagcggcggacgggugaguaacgc
gugggugaccuacccggaagagggggacaacccggggaaacucgggcuaa
ucccccauguggacccgccccuugggguguguccaaagggcuuugcccgc
uuccggaugggcccgcgucccaucagcuaguuggugggguaauggcccac
caaggcgacgacggguagccggucugagaggauggccggccacaggggca
cugagacacgggccccacuccuagggaggcagcaguuaggaaucuuccgc
aaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccuuc
gggguguaaacuccugaacccgggacgaaacccccgacgaggggacugac
gguaccgggguaauagcgccggccaacuccgugccagcagccgcgguaau
acggagggcgcgagcguuacccggauucacugggcguaaagggcguguag
gcggccuggggcgucccaugugaaagaccacggcucaaccgugggggagc
gugggauacgcucaggcuagacggugggagagggugguggaauucccgga
guagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggcag
ccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaacc
ggauuagauacccggguaguccacgcccuaaacgaugcgcgcuaggucuc
ugggucuccugggggccgaagcuaacgcguuaagcgcgccgccuggggag
uacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaagc
gguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccaggcc
uugacaugcuagggaacccgggugaaagccuggggugccccgcgagggga
gcccuagcacaggugcugcauggccgucgucagcucgugccgugaggugu
uggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcggu
ucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggaggg
gacgacgucuggucagcauggcccuuacggccugggcgacacacgugcua
caaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgcaa
aaaggugggcccaguucggauuggggucugcaacccgaccccaugaagcc
ggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguucccg
ggccuuguacacaccgcccgucacgccaugggagcgggcucuacccgaag
ucgccgggagccuacgggcaggcgccgaggguagggcccgugacuggggc
gaagucguaacaagguagcuguaccggaaggugcggcuggaca
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<...<<.<........>.>>.>>......<<.......<<
<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>....
.>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>>.>
>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<...>>>>...>>>>>>>........<<<.
...<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<...
.>>>>.....>>>>....<<<<<..........<<.....>>........
....>>>>>......<<<<<(((...<<<<<.....<<.)))>>......
.>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<...<
<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>>
>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<.
<..<<<......>>>.....>.>>>>>>>...........<<....>>.>
>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...<<
<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<<<
<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<...
...<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
......<<<<<<<<..<<<<<<<....>>>>>>>.....<......>...
.>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..
<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<...<<<.
....>>>>.....>>>>>>>.....<<<<<....>>>>>........>>>
>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.
....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>..
...>>>>>>>...........<<<<<<<........>>>>>>>.......
...>>>>>>....<<<<<<<..........>>>>>>>......>>...>>
>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<...<
.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>.>>>
>..>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB5el5 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		A2 R3 R4 R5 R6 A7 R10 N28 K29 I30 M31 R32 D33 G34 K36 N37 L38 R41 I42 R76 R79 R94 S98 R102 R114 R115 A116 R119
Binding residue
(residue number reindexed from 1)		A1 R2 R3 R4 R5 A6 R9 N27 K28 I29 M30 R31 D32 G33 K35 N36 L37 R40 I41 R75 R78 R90 S94 R98 R110 R111 A112 R115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5el5, PDBe:5el5, PDBj:5el5
PDBsum5el5
PubMed26791911
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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