Structure of PDB 5e81 Chain 69 Binding Site BS01

Receptor Information
>5e81 Chain 69 (length=145) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVILLEPLENLGDVGQVVDVKPGYARNYLLPRGLAVLATESNLKALEAR
IRAQAKRLAERKAEAERLKEILENLTLTIPVRAGETKIYGSVTAKDIAEA
LSRQHGVTIDPKRLALEKPIKELGEYVLTYKPHPEVPIQLKVSVV
Ligand information
>5e81 Chain 13 (length=1496) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuuuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccguggucagcggcggacgggugaguaacgc
gugggugaccuacccggaagagggggacaacccggggaaacucgggcuaa
ucccccauguggacccgccccuugggguguguccaaagggcuuugcccgc
uuccggaugggcccgcgucccaucagcuaguuggugggguaauggcccac
caaggcgacgacggguagccggucugagaggauggccggccacaggggca
cugagacacgggccccacuccuacgggaggcagcaguuaggaaucuuccg
caaugggcgcaagccugacggagcgacgccgcuuggaggaagaagcccuu
cgggguguaaacuccugaacccgggacgaaacccccgacgaggggacuga
cgguaccgggguaauagcgccggccaacuccgugccagcagccgcgguaa
uacggagggcgcgagcguuacccggauucacugggcguaaagggcgugua
ggcggccuggggcgucccaugugaaagaccacggcucaaccgugggggag
cgugggauacgcucaggcuagacggugggagagggugguggaauucccgg
aguagcggugaaaugcgcagauaccgggaggaacgccgauggcgaaggca
gccaccugguccacccgugacgcugaggcgcgaaagcguggggagcaaac
cggauuagauacccggguaguccacgcccuaaacgaugcgcgcuaggucu
cugggucuccugggggccgaagcuaacgcguuaagcgcgccgccugggga
guacggccgcaaggcugaaacucaaaggaauugacgggggcccgcacaag
cgguggagcaugugguuuaauucgaagcaacgcgaagaaccuuaccaggc
cuugacaugcuagggaacccgggugaaagccuggggugccccgcgagggg
agcccuagcacaggugcugcauggccgucgucagcucgugccgugaggug
uuggguuaagucccgcaacgagcgcaacccccgccguuaguugccagcgg
uucggccgggcacucuaacgggacugcccgcgaaagcgggaggaaggagg
ggacgacgucuggucagcauggcccuuacggccugggcgacacacgugcu
acaaugcccacuacaaagcgaugccacccggcaacggggagcuaaucgca
aaaaggugggcccaguucggauuggggucugcaacccgaccccaugaagc
cggaaucgcuaguaaucgcggaucagccaugccgcggugaauacguuccc
gggccuuguacacaccgcccgucacgccaugggagcgggcucuacccgaa
gucgccgggagccuacgggcaggcgccgaggguagggcccgugacugggg
cgaagucguaacaagguagcuguaccggaaggugcggcuggacacc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..
<<<.<<<..<<<..<<.<<......>>.>>>>>......<<.......<<
<<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>....
.>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<<<<...>>>>.>
>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<.......>>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<....>>>>...>>>>>>>........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<..
..>>>>.....>>>>....<<<<<........<<<<.....>>>>.....
.....>>>>>......<<<<<(((...<<<<<.....<<.)))>>.....
..>>>>>>>>>>..>>>>>>>>>..........<<<((.....<<<<...
<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.....>>>>>>....>
>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<
.<..<<<......>>>.....>.>>>>>>>...........<<....>>.
>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...<<...<
<<<.........>>>>...>>>>>>>>..........<<<<<<..<<<<<
<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<..
....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<
<<<<..<<<<<<<<<<......<<........>>..........<<<<<<
<......<<<<<<<<..<<<<<<<....>>>>>>>...............
..>>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>.
.<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..<<<..<<<
.....>>>>>>...>>>>>>>.....<<<<<....>>>>>........>>
>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>
.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>.
....>>>>>>>......<..<.<<<<<<<........>>>>>>>>...>.
....>>>>>>....<<<<<<<..........>>>>>>>......>>...>
>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<...
<.<<<<....<<<....>>>.>>>>.>..>>>>>>>>>>>>>..>>>.>>
>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5e81 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		R82 K87 Y89 G90 S91 K121
Binding residue
(residue number reindexed from 1)		R82 K87 Y89 G90 S91 K121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5e81, PDBe:5e81, PDBj:5e81
PDBsum5e81
PubMed26791911
UniProtQ5SLQ1|RL9_THET8 Large ribosomal subunit protein bL9 (Gene Name=rplI)

[Back to BioLiP]