Structure of PDB 6zvk Chain 62 Binding Site BS01 |
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| >6zvk Chain e2 (length=3920)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau
guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcggguccggccgugucggcgg
cccggcggaucuuucccgccccccguggggucggcgggggaccguccccc
gaccggcgaccggccgccgccgggcgcauuuccaccgcggcggugcgccg
cgaccggcuccgggacggcugggaaggcccggcggggaagguggcucggg
gggccccgcgggaccgaaaccccccccgaguguuacagcccccccggcag
cagcacucgccgaaucccggggccgagggagcgagacccgucgccgcgcu
cuccccccucccggcgcccacccggggcgcgccggcgucuccucgugggg
gggccgggccaccccucccacggcgcgaccgcucucccaccccucgucgg
ggggcggggcggacuguccccagugcgccccgggcgggucgcgccgucgg
gcccgggggagguucucucggggccacgcgcgcgucccccgaagaggggg
acggcggagcgagcgcacggggucggcggcgacgucggcuacccacccga
cccgucuugaaacacggaccaaggagucuaacacgugcgcgagucggggg
cucgcacgaaagccgccguggcgcaaugaaggugaaggccggcgcgcucg
ccggccgaggugggaucccgaggccucuccaguccgccgagggcgcacca
ccggcccgucucgcccgccgcgccggggagguggagcacgagcgcacgug
uuaggacccgaaagauggugaacuaugccugggcagggcgaagccagagg
aaacucugguggagguccguagcgguccugacgugcaaaucggucguccg
accuggguauaggggcgaaagacuaaucgaaccaucuaguagcugguucc
cuccgaaguuucccucaggauagcuggcgcucucgcagacccgacgcacc
cccgccacgcaguuuuauccgguaaagcgaaugauuagaggucuuggggc
cgaaacgaucucaaccuauucucaaacuuuaaauggguaagaagcccggc
ucgcuggcgugagccgggcguggaauggagugccuagugggccacuuuug
guaagcagaacuggcgcugcgggaugaaccgaacgccggguuaaggcgcc
cgaugccgacgcucaucagaccccagaaaagguguugguugauauagaca
gcaggacgguggccauggaagucggaauccgcuaaggaguguguaacaac
ucaccugccgaaucaacuagcccugaaaauggauggcgcuggagcgucgg
gcccauacccggccgucgccggcagucgagaguggacgggagcggcgggg
gcggcgcgcgcgcgcgcccgcccccggagccccgcggacgcuacgccgcg
acgaguaggagggccgcugcggugagccuugaagccuagggcgcgggccc
ggguggagccgccgcaggugcagaucuuggugguaguagcaaauauucaa
acgagaacuuugaaggccgaaguggagaaggguuccaugugaacagcagu
ugaacaugggucagucgguccugagagaugggcgagcgccguuccgaagg
gacgggcgauggccuccguugcccucggccgaucgaaagggagucggguu
cagauccccgaauccggaguggcggagaugggcgccgcgaggcguccagu
gcgguaacgcgaccgaucccggagaagccggcgggagccccggggagagu
ucucuuuucuuugugaagggcagggcgcccuggaauggguucgccccgag
agaggggcccgugccuuggaaagcgucgcgguuccggcggcguccgguga
gcucucgcuggcccuugaaaauccgggggagaggguguaaaucucgcgcc
gggccguacccauauccgcagcaggucuccaaggugaacagccucuggca
uguuggaacaauguagguaagggaagucggcaagccggauccguaacuuc
gggauaaggauuggcucuaagggcugggucggucgucggccggcgccuag
cagccgacuuagaacuggugcggaccaggggaauccgacuguuuaauuaa
aacaaagcaucgcgaaggcccgcggcggguguugacgcgaugugauuucu
gcccagugcucugaaugucaaagugaagaaauucaaugaagcgcggguaa
acggcgggaguaacuaugacucucuuaagguagccaaaugccucgucauc
uaauuagugacgcgcaugaauggaugaacgagauucccacugucccuacc
uacuauccagcgaaaccacagccaagggaacgggcuuggcggaaucagcg
gggaaagaagacccuguugagcuugacucuagucuggcacggugaagaga
caugagagguguagaauaagugggaggcccccggcgcccccccggugucc
ccgcgaggggcccggggcgggguccgccggcccugcgggccgccggugaa
auaccacuacucugaucguuuuuucacugacccggugaggcgggggggcg
agccccgaggggcucucgcuucuggcgccaagcgcccggccgcgcgccgg
ccgggcgcgacccgcuccggggacagugccagguggggaguuugacuggg
gcgguacaccugucaaacgguaacgcagguguccuaaggcgagcucaggg
aggacagaaaccucccguggagcagaagggcaaaagcucgcuugaucuug
auuuucaguacgaauacagaccgugaaagcggggccucacgauccuucug
accuuuuggguuuuaagcaggaggugucagaaaaguuaccacagggauaa
cuggcuuguggcggccaagcguucauagcgacgucgcuuuuugauccuuc
gaugucggcucuuccuaucauugugaagcagaauucaccaagcguuggau
uguucacccacuaauagggaacgugagcuggguuuagaccgucgugagac
agguuaguuuuacccuacugaugauguguuguugccaugguaauccugcu
caguacgagaggaaccgcagguucagacauuugguguaugugcuuggcug
aggagccaauggggcgaagcuaccaucugugggauuaugacugaacgccu
cuaagucagaaucccgcccaggcggaacgauacggcagcgccgcggagcc
ucgguuggccucggauagccggucccccgccuguccccgccggcgccgcg
cgccgggaccgggguccggugcggagugcccuucguccugggaaacgggg
cgcggccggagaggcggccgcccccucgcccgucacgcaccggccguucg
uggggaaccuggcgcuaaaccauucguagacgaccugcuucugggucggg
guuucguacguagcagagcagcucccucgcugcgaucuauugaaagucag
cccucgacacaaggguuugu |
.........................<<<<<<<....<......>.....>
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[....<<<...<<<<<<<<<<<...>>>>>>>.>>>>...
..>>>....<<<<<<<<<....<<<<<<<<.<.<....<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>>.>>>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>
>>>>.....(((((..<<<<<<)))))..]]]..................
................<<....>>...............<<<......>>
>..................................<<<<<<<<..<<<..
....<<<<<<<<.<<<.....<<<<<<<<<<<...<<<.....<<<<.<<
....<<<<.<<<..<<<<<<<<<<..>>>>..>>>>>>>>>>>>>>>.>>
>>.......>>>.>>>>>>>>>>>......>>>.>>>.>>>>>..<<<<<
<<..<<<<<<<<<<.<<<....<.....<<<<.<<<<......<<<<<<<
.<....<..>...........>>..>>>>>>.......>>>>.>>>>...
.......>.>>>...>>>>>>>>>>....................<<<<.
..<<<<<<<..<<<<<....<<<.>>>..>>>>>.<<......>>.>>>>
>>>.....<<.<<<<.<<<<<<<<<<<<<<<<<.......<<<<.....>
>>>.<<<<<<<.<<<<....>>>>.>>>>>>>>>>.>>>>>>>>>>>.>>
>...>.>>>...........>.>.........<<<<<<<<.....>>>>>
>>>.........>>>>.......>>.>>>>>....>>>...>>>>>>>>.
.<<<<........>>>><<<<<<....<<<<<<<<<<<<<..<<<...<<
<<........>>>>.....>>>...<<....>>...<<<<<<<......>
>>>>>>..<<<<<...<<<..<<<...(((..[..>>>..>>>....>>>
>>.<<<<<<<<<.<<<<......>>>>>>>>>>>.>>....>>>>>>>>>
>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<.
...>>>>>>>.....>>>...<<<..<<.<<........>>>>.>>>...
.>>>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<<
<<<<....<.<<<....>>>.><<<<<<<<<<..................
.........<<.<<<<<<<<<...<<<....<<<..<.<<<..<....<.
........>...>.>>>.>..>>>..>.>>...>>>>>>>...<<<<<<<
<<........>>>>>>>>>...>>.>>>>>>>>>.>>>..<<<<.<<<<<
.....>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<(((
.......<<<<<.....<<..........<<<.<<<<<<<<<<.......
<<....<<....<<.........>>....>>.......<.<<......>>
.>....>>...>>>>>>>>>>>>>..........))).>>...>>>>>..
>>>...>>>>>>><<<<<<.<<<............].)))..........
............................................>>>>>>
>>>....>>>>>>.<<<<<<<<<<.<<......<<<<.<<<<....>>>>
>>>>...>>>>>>>>>>.>>.....>>>>>><<<....<<.....<<<<<
<.......>>>>>>.<<<.....<<<<<.<<...<<<<<<...<<.....
>>.>>>>>>....((<<<<<<...<<....<<<....>>>..........
<<.<<<<<<<<<...>>>>>>>>>>>......>>....>>>..<<<<<..
......>>>>>))<<<<....<<<<...<<<<<<<<....>>>>>>>>..
<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<.<<<<<<<<<<.
.{{{..>>>>>>....<<<<<.<<<<.<<<<.....<<<.....>>>...
..>>>>>>>>..>>>>>.....<<<<<<<.......>>>>>>>>>>>...
>>>>>>>>>>>>.........>>>>>>>..>..........>..>>>.>>
>>.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>.
...<<<<.....<<<<<<<.<<.........<.....<<<<<....<<..
>>.....>>>>><<.<<<<<<<<<<<..<<<<<<<.>>>>>>>.......
>>>>>..>>>>>>.>>............<<<<<<<<<..<<<........
.>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..
<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>.>>>>..
>>>>><<<<<<.......>>>>>>........<...........<<<<<.
......>>>>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>
>>>..>>>>>>...>>>....<<<<<........>>>>>....[[[[[..
{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<.<<
<...............................<<<<.<<<<<<<<.<<<<
<.....>>>>>>>>>>>..>>...>>>>......................
.................>>>.>>>>>>...<<<<<.....<<<<..<<.<
<<<<<<..>>>>>>>>>..............<<<<<<<<<<<.....>>>
>>>>>>>>..>>>>..>>>>>....>>>>>>>>>..>>>>>...<<<...
..>>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<
<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<..
<<<<.......>>>>..>>>.<<<....>>>.>>)))]......((((((
..(((..>>>>>>.)))))))))..........]]]]..}}]]]].....
..<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>...
....<<<<<.<<<<<<..<.<.<<<<<......>>>>>...>.>.<<<..
.......>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>
.>>>>....}}..}}}.]]]]].....<<<<<<....<<<..<.<<<<<.
................>>>>>.><<<<....<<<<....<<.<<<<<<.}
}}..>>>>..>>.>>...>>>>...>>>><<<<<...<<<<<........
...>>>>>...>>>>>.>>>.....>>>>>>.....<<<<<<<.....<<
<.....<<.........<<<<<..<.<<....<<<<<.<<<<<..>>>.>
>...>>>>>..>>>.>>>>>........>>....<<..<<<<....<<<<
.<<<<<<<......>>>>>>>>>>>...>>>>..>>..............
..>>>....>>>>>>><<<<<.<.............>....<<.<<<<<<
<.<<.....<<<<.<..<<<<<......>>>>>..>>>>>....>>....
>>>>.>>>.>>..>>>>>.. |
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| PDB | 6zvk The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. |
| Resolution | 3.49 Å |
Binding residue
(original residue number in PDB) | K2 S4 Y63 F68 P72 S86 R87 N92 Y94 R111 G114 A115 R116 H117 R118 R120 R139 H146 S148 P155 H156 R157 L159 R160 R161 Q162 K164 P165 R166 T168 T169 K170 P172 N173 T174 F175 F176 |
Binding residue
(residue number reindexed from 1) | K1 S3 Y62 F67 P71 S85 R86 N91 Y93 R110 G113 A114 R115 H116 R117 R119 R138 H145 S147 P154 H155 R156 L158 R159 R160 Q161 K163 P164 R165 T167 T168 K169 P171 N172 T173 F174 F175 |
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| Enzyme Commision number |
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