Structure of PDB 8om3 Chain 6 Binding Site BS01

Receptor Information
>8om3 Chain 6 (length=319) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FSRRRIAYPFYPFKKLGRQHPKKHDTNLKTAMRQFLGPKNYKGEYVMNKY
FTVPTNHVPNYIKPDLERGQSLEHPVTKKPLQLRYDGTLGPPPVENKRLQ
NIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEEITVEGLSAQQVSQKYG
LKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMDETLYRMFPVFDSDASFK
RENLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLELEPAVETLRNLST
VGEHSSGHQQSTNKNTKVIYGELVEGERSQYKFTNAKVGKVGYRYGSGNR
DNKKDRRIGFNKLGQMVYI
Ligand information
>8om3 Chain r (length=1487) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacac
augcgaaucauacguuuauuauugauaagauaauaaauaugugguguaaa
cgugaguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacu
uaauauauaaaaaggauauauaauauauuuaucuauagucaagccaauaa
ugguuuagguaguagguuuauuaagaguuaaaccuagccaacgauccaua
aucgauaaugaaaguuagaacgaucacguugacucugaaauauagucaau
aucuauaagauacagcagugaggaauauuggacaaugaucgaaagauuga
uccaguuacuuauuaggaugauauauaaauauauauauauaaauugauua
aaaauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauu
uuuauauggauauauuuuaauaguccugacuaauauuugugccagcaguc
gcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauccg
uagaaugaauuauauauuauaauuuagaguuaauaaaauuaauuaaagaa
uuauaauaguaaagaugaaauaaauaauuauaagacuaauauaugugaaa
auauuaauuaaauauuaacugacauugagggauuaaaacuagaguagcga
aacggauucgauacccguguaguucuaguaguaaacuaugaauacaauua
uuuauauauauauauauaaauaauaaaugaaaaugaaaguauuccaccug
aagaguacguuagcaauaaugaaacucaaaacaauagacgguuacagacu
uaagcaguggagcauguuauuuaauucgauaauccacgacuaaccuuacc
auauuuugaauauuauaauaauuaaauuauuauauuacaggcguuacauu
guugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaacgaac
aaaacuccauauauauaauuuuaauuauauauaauuuuauauuauuuauu
aauauaaagaaaggaauuaagacaaaucauaaugauccuuauaauauggg
uaauagacgugcuauaauaaaaugauaauaaaauuauauaaaauauauuu
aauuauauuuaauuaauaauauaaaacauuuuaauuuuuaauauauuuuu
uuauuauauauuaauaugaauuauaaucugaaauucgauuauaugaaaaa
agaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacu
guuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauua
uuuauauaauauuuuuuaauaaauuuauuaauuuauauuuauuuauauca
gaaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaac
cugcggugggcuuauaaauaucuuaaauauucuuaca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<
.<<<..<<<..<<<<<<<<<<<<.....>>>>>>>>>>..>>>>>.....
<<<........<<<<<.<<.........<<<<<<<<.<<<<.......>>
>>...........<<<<<<<<.>>>>>>>>.>>>>>>>>....>>>>>>>
<<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>..
<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>><
<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>..
>>>...>.>>>>>>.<<<<..<<<<<<........>>>>>>..<<.....
.>>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..
..>>>>>>><<..>>>>>....<<<<<(((.....<<<<.....<<.)))
>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<<.
..<.<<.<<<<<<<...>>>>>>>...<<<<<<<<...<<<<<<<<<<..
<<<<<<<...................>>>>>>>..>>.......<<....
>>.>>>>>>>>.>>>>>>>>...>>>...>>>>....<<<<<<...<<..
.<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.<<<<
<<<<<<<<<..>>>>>>>>>>>>>..<<..))>>....>>>>>>.>>>.<
<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<<...
..<<<<<<..<<<<<<<<<<......<<........>>..........<<
<<<<<.....<<.<<<<<<<<<<.>>>>>>>>>>.>>.<<<.<<<..<<<
<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>>>>>>
.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.....>
>>>>>>>>....>>>...>>>>>.>>>...>>>>>>>>>...>>>>>>>.
..>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<<<...
...>>>>>>..>>....>>>......>>>>>>......<<<<<.......
.>>>>>..........<....<<<<<<<........>>>>>>>....>..
...>>>>>>....<<.<<<<<.........>>>>>>>...........>>
>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<
<..<<<.<<<<<...<<<<<<<..>>>>>>>...>>>>>>>>..>>>..>
>>>>>>>>>>>..>>>>>>>>..>.>>>..>.....<<<<<<<<<....>
>>>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8om3 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Resolution2.87 Å
Binding residue
(original residue number in PDB)
S28 R29 R30 Y34 F39 K41 L42 R44 Q45 P47 K48 K49 H50 T52 N53 K55 K65 N66 Y67 M73 H100 P101 S194 R198 R200 R304 G322 G324 N325 R326 D327 N328 K329 K330 R332 Y344
Binding residue
(residue number reindexed from 1)
S2 R3 R4 Y8 F13 K15 L16 R18 Q19 P21 K22 K23 H24 T26 N27 K29 K39 N40 Y41 M47 H74 P75 S168 R172 R174 R278 G296 G298 N299 R300 D301 N302 K303 K304 R306 Y318
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8om3, PDBe:8om3, PDBj:8om3
PDBsum8om3
PubMed38199006
UniProtP53292|RT35_YEAST Small ribosomal subunit protein mS45 (Gene Name=MRPS35)

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